About the 5-year fibrel study.
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Biomedical subjects
Publications and source records attributed to D E Gormley.
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Cutaneous surgery in 34 pregnant women is described. The main indication for surgery was the diagnosis and/or treatment of malignancy. Surgery during the period of organogenesis (15 to 56 days) should be avoided when possible. Patients should be positioned on the left side during the procedure to avoid the supine hypotensive syndrome. Monitoring of the fetal heartbeat is desirable. Local anesthetics, penicillin, and erythromycin are safe if used carefully. Acetaminophen is the analgesic of choice. Exposure to the sun should be avoided during the perioperative period.
We report the results obtained from 18 women whose facial folds and furrows were treated with augmentation therapy. The results of treatment with microlipoinjection and injectable collagen were measured and compared at regular intervals for a period of 1 year using a method of optical profilometry. Subsidence was noted with both modalities. Collagen gave consistent results. Seventy-five percent of correction on the average is lost at 6 months, but 22% of the collagen-treated subjects maintained at least 30% correction 1 year from the time of treatment. Autologous fat gave unpredictable results ranging from poor to excellent. A good result at 6 months is likely to be maintained until 1 year from the time of treatment. Forty-four percent of fat augmented subjects maintained at least 30% correction 1 year after treatment.
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This article presents solutions to difficult surgical repair problems. Solutions for the repair of defects in the ear (in this case the ear lobule) and upper lip are discussed. A solution is also provided for an exasperating problem that arises when cheek and neck lifts are done. An aid for the design of cutaneous flaps is shown, and an improvisation that can be used for the closure of wounds near the nose and upper lip is presented. Properly used, this technique can enhance the cosmetic result of wound closures that might otherwise distort the ala nasi or structures near the lip.
We present three patients with Bowen's disease of the fingernail folds and beds in which there was polydactylous involvement and add those to five similarly afflicted patients described by other authors. Bowen's disease of the nail is a distinctive type of squamous cell carcinoma that differs from other variants. It is potentially an autochthonous process that can involve more than one nail with the passage of time. Seven-eighths of the patients described in this series were men. A majority had involvement of both hands. No metastases were seen.
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Controlled tissue embedding is a method which facilitates the histologic search of margins of excised skin and subcutaneous tissue for evidence of tumor extensions. Used on frozen unfixed specimens, data obtained from a study of 141 sections made from 32 excised tumors show that controlled embedding allows for adequate assessment of surgical margins in less time and with less tissue cutting as compared to conventional methods.
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Burow's wedge flap provides an excellent method for repair of wounds in or near the eyebrow. Advantages afforded by this technic in this context include ample flap elasticity and vascularization, versatility in dealing with wounds of varying dimension and location, and fewer incisions in comparison with the number necessary with other methods. Between 1980 and 1984 the author used this method in twelve patients and obtained good to excellent results in eleven and a fair outcome in one.
The Burow's wedge/triangle principle is analyzed and related to a variety of closure techniques that bear various names. The rationale for the application of these principles is reviewed.
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Three examples of an unusually aggressive form of basal cell carcinoma in the skin of the scalp were treated surgically. The extent of each tumor was verified with gross and microscopic examination. The tumors invaded fat, muscle, fascia, and bone. Dural involvement was seen in one case. Light microscopy showed a marked variation in growth patterns and cytologic types from one portion of the tumor to another. Characteristics included a diffusely infiltrating pattern with a fibrotic stromal response, rare intraepidermal tumor nests, formation of occasional duct-like structures, poor cellular cohesion with single-life invasion through dermal collagen, perineural invasion, and pleomorphism with varying nuclear cytoplasmic ratios. Basaloid populations with peripheral palisading were seen in each tumor. These malignancies may be representative of an unusual basal cell carcinoma variant unique to the scalp.
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An analysis of the geometric and mechanical factors leading to the formation of dogears at the ends of surgical wounds in the skin is presented. Corrective measures are discussed.