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Biomedical subjects

D E Fitzgerald

Publications and source records attributed to D E Fitzgerald.

34 records · Page 2Linked to original sources
PubMed1977

Peripheral arterial disease: assessment by arteriography and alternative noninvasive measurements.

In most centers arteriography is the sole method used to investigate peripheral arterial disease. In view of the availability of other noninvasive techniques, this practice must be reappraised. Among 3,000 patients with peripheral arterial disease, 40% of those undergoing arteriography were found unsuitable for reconstructive arterial surgery primarily because of poor arterial runoff. Noninvasive assessment techniques are discussed, including sequential arterial scanning with Doppler ultrasound. In a single-blind comparison of Doppler ultrasound scanning and arteriography, findings by ultrasound were confirmed by arteriography in 265 of 267 examinations. Blood pressure measurements in the limbs as well as fluorescence and radioisotope clearance studies also provide valuable information. It is recommended that a more rational approach to the assessment of peripheral arterial disease be considered, particularly in elderly patients, to safeguard against undue discomfort and risk. Arteriography should be reserved for patients undergoing reconstructive surgical procedures.

Aged↗
PubMed1966

Abdominal venous pump.

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Blood Pressure Determination↗
PubMedDate not supplied

Mean flow velocity in the right common carotid artery before and after maximal exercise.

The effect of exercise on mean flow velocity (MFV) in the right common carotid artery (RCC) was studied using pulsed Doppler ultrasound. MFV was measured at rest and at 2 minutes intervals after a 6 minute rowing ergometer test. Age-related maximum heart rate of 190 +/- 10 beats.min-1, maximum respiratory rate of 60 +/- 5 breaths.min-1, and postexercise lactate level of greater than 8 mmol.l-1 were the criteria used to define maximal exercise. The control group comprised 13 healthy, active males, mean age 19.8 years, with 19 healthy oarsmen, mean age 19.9 years, in the exercise group. At rest, MFV in the RCC was found to be 18.6 +/- 5.6 and 16.4 +/- 6.3 cm.min-1 in the control and exercise groups respectively. After exercise, MFV decreased to 21% of its resting value and remained significantly reduced (posthoc tests, Newman Keuls at alpha = 0.01) until 14-16 minutes of recovery. Mean systemic arterial pressure (MSAP) remained within normal limits. Mean age-related maximum heart rate was 182 +/- 3 beats.min-1, respiratory rate 58 +/- 3 breaths.min-1, and postexercise serum lactate 20.2 +/- 3.5 mmol.l-1 which satisfied the criteria for maximal exercise. In this group of young males, MFV in the RCC decreased markedly after maximal exercise and remained significantly reduced for a long period. This sustained reduction in MFV has not previously been described and is most likely due to vasoconstriction in distal cerebral resistance arterioles mediated by hypocapnia and autonomic activity.

Adult↗