Biomedical subjects
Publications and source records attributed to D E Barnardo.
A primary carcinoid tumor of the mesentery was associated with intestinal obstruction in a 74-year-old man. Increased levels of plasma pancreatic polypeptide were subsequently demonstrated. An autopsy performed four years later showed carcinoid metastatic dissemination and confirmed the primary mesenteric origin of the carcinoid tumor initially resected at surgery.
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Five cases of diffuse gastric spiculation seen on single contrast barium meal examination are reported. This appearance may spuriously suggest superficial mucosal ulceration in cases in which no evidence of this is found endoscopically or histologically. This radiological appearance may be due to filling of the grooves between the areae gastricae and may thus represent a normal anatomical variant.
In a double-blind trial in 26 patients with symptomatic gastro-oesophageal reflux, the alginate/effervescent/antacid compound 'Gaviscon' was compared with antacid containing placebo similarly formulated. Retrosternal pain after meals and at night was significantly reduced whilst patients were taking 'Gaviscon' and the beneficial effects lasted for many weeks after discontinuation of the active preparation.
A prospective study of serum bilirubin levels on the first and sixth days of life in a series of 181 infants has failed to provide evidence to suggest that previous maternal oral contraception, maternal oxytocin infusion, epidural anaesthesia, or breast-feeding are factors influencing neonatal jaundice.
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True arthritis is very much less common than arthralgia in patients suffering from active chronic hepatitis and only scanty information is available about the joint changes in this disease. We report here the case of a young woman with active chronic hepatitis complicated by a painless, erosive small joint arthropathy.
A case of sarcoidosis with involvement of the rectum is described. This is believed to be the first unequivocal case of large bowel sarcoidosis.
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