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Biomedical subjects

D Durand

Publications and source records attributed to D Durand.

393 records · Page 22Linked to original sources
PubMedDate not supplied

[Growth hormone in adults. An elixir of youth?].

Studies have revealed a partial deficiency of growth hormone (GH) secretion in the elderly. Aging has a central effect on the GH secretion and probably a peripheral effect on insulin-like growth factor 1 (IGF-1) or somatomedin C through changes in body composition. Simultaneously therapeutic efficiency of recombinant GH was confirmed in adults with GH deficiency. These notions have led to some controlled trials of GH treatment in elderly. Further studies of GH replacement are needed, examining issues such as dosage, tolerance (still inadequate) and efficacy before the widespread use of GH or IGH-F 1 in the elderly is advocated.

Adult↗
PubMedDate not supplied

[An accident related to a seat belt. Lymphocoele and extrinsic stenosis of the ureter in a transplant patient. Reparative surgery (author's transl)].

Trauma to a graft by a seat belt in a young adult, 18 months after transplantation. Drainage shortly after of a voluminous perirenal haematoma, abundant discharge of lymphorrhoea taking two months to resolve. Good recovery of the graft from both a radiological as well as biological standpoint. 4 years after the trauma, leucocytes in the urine associated with impairment of function of the graft. Discovery of a large hydronephrosis related to retro-peritoneal fibrosis. Ureterolysis with resection of the affected part of the ureter followed by anastomosis. Return to normal of renal function with disappearance of the hydronephrosis. Lymphocoele, a rare complication of renal transplantation, is discussed from three viewpoints: aetiopathology, diagnosis and treatment.

Accidents, Traffic↗