Biomedical subjects

D Dumitrescu

Publications and source records attributed to D Dumitrescu.

38 records · Page 3Linked to original sources

PubMedDate not supplied

Remarks on the pathogenic significance of HBsAg subtypes.

The frequent controversies concerning the possible different pathogenic significance of antigenic hepatitis B virus subtypes determined the authors to analyse the mean values of some biochemical tests in two groups of acute viral hepatitis patients. The results obtained show that a more marked alteration of these values is correlated with the presence of HBsAg/ay in one of the groups (89 patients) and with that of HBsAg/ad in the other group (33 patients). Some explanations of these findings are suggested.

Acute Disease↗

PubMedDate not supplied

Some sex- and age-dependent correlations in acute viral hepatitis.

HBsAg was found to be present in 28.7% of 1980 sera from acute viral hepatitis (AVH) patients tested by immunodiffusion and counterimmunoelectrophoresis. The incidence of HBsAg-positive AVH cases was lower in female subjects aged 10-19 years. The follow up of SGPT, bilirubinemia and thymol turbidity kinetics in 473 of the patients revealed some HBsAg-dependent differences. Such differences oscillated more markedly in adults than in children and were less obvious in women. The possible involvement of certain individual factors in the determinism of hepatitis B virus infection and of its further evolution is suggested.

Adolescent↗