Biomedical subjects
D Delafontaine
Publications and source records attributed to D Delafontaine.
["In vitro" glass fiber filtration of sperm (author's transl)].
Filtering sperm through glass fiber has been suggested as a method for improving its fecundity before homologous artificial insemination. Various technical modification of this procedure have enabled good results to be obtained on spermatozoid mobility but at the expense of a marked drop in numbers: sperm counts per ml are diminished by a half. A comparative in vitro study of the penetration of filtered and non-filtered sperm into the cervical mucus showed that glass fiber filtration produced generally no great improvement, and may indeed reduce penetration into the cervical mucus to a marked degree in some cases.
[Effect on fertility of MOPP treatment of Hodgkin's disease].
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[The correlation between the results of caryotype studies and sperm counts. 119 cases (author's transl)].
119 patients had sperm counts and caryotyping performed. Seven out of 33 azoospermic patients had a major caryotype abnormality of the gonosomes. Five out of 86 subjects who were not azoospermic had a persistent translocation and other moderate abnormalities in the sperm picture.
[Insemination (IAC) with fractionated ejaculate in sterile couples. Spermatological, hormonal and clinical considerations in 73 cases].
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[Does inhibin play a role in the acquisition of spermatozoa motility?].
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[Sperm preservation for young cancer patients].
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[Hydronephrosis revealing a left pararenal teratoma].
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Unexplained infertility: a new syndrome: multiple immature luteinized follicles (MILF) syndrome.
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[Intra-uterine pregnancy after microsurgical salpingostomy for bilharziasis of the tubal ampulla].
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[Oocyte maturity and quality: value of intracytoplasmic sperm injection. Fertility of microinjected oocytes after in vitro maturation].
Many studies in IVF practice, have tried to assess the maturity and quality of oocytes prior to insemination and relate it to IVF efficiency and to the pattern of ovarian stimulation. They were based on the indirect evaluation of the aspect of the cumulus-corona-cell complex (CCC) which was rapidly shown to be poorly correlated to the oocyte nuclear and cytoplasmic maturity in stimulated cycles. For sperm microinjection procedures, oocytes need to be peeled off from any follicular cell through hyaluronidase action in order to gain an easy access to the zona pellucida and the ooplasm. If therefore becomes possible to precisely known at recovery the nuclear status of the oocyte cohort as well as the rate of degenerative gametes. Immature oocytes can be further matured in vitro. Moreover, the ICSI procedure (intracytoplasmic sperm injection) allows a direct assessment of the cytoplasmic maturation, whatever the maturity of the ZP and its receptors and of the plasma membrane. On a preliminary evaluation of 70 ICSI cycles performed in our collaborative group from september to november 1994 and leading to a 24 % pregnancy rate per oocyte pick-up we focused on the true maturation of the oocyte cohort, its outcome and correlation with ICSI efficiency and stimulation protocol. On the 760 oocytes, 13.9% were atretic, 9% at the germinal vesicle stage (GV), 3.4% in metaphase 1 and 73.7% in metaphase 2 at recovery.(ABSTRACT TRUNCATED AT 250 WORDS)