Search PubMed⌕ Search

Biomedical subjects

D Daniel

Publications and source records attributed to D Daniel.

At least 55 records · Page 3Linked to original sources
PubMed1985

Radical wedge resection for ingrown toenail: long-term results.

This paper describes an operation for ingrown toenail that is simple, has a low recurrence rate, leaves patients with an intact, pain-free, cosmetically acceptable nail-bearing toe, and permits the wearing of normal shoes within a short period of time. Among the numerous techniques devised for the treatment of ingrown toenail, no other operation fulfills all of these criteria. It is usual to sacrifice appearance in the hope of cure. During the last 20 years we have adopted a radical wedge resection that has the advantage of resulting in permanent healing and a good-looking toe. After a first series of 67 cases thus treated without a single recurrence, the technique was used in a further series of 339 cases reported here.

Adolescent↗
PubMed1982

The diagnosis of meniscus pathology.

A study of 281 patients evaluated for a meniscus pathologic condition was performed to assess the accuracy of the clinical diagnosis and arthrogram and delineate the role of arthroscopy. Following the clinical examination, the surgeon stated his level of confidence in his diagnosis, as did the radiologist in his interpretation of the arthrogram. In 134 cases inspected by arthroscopy or arthrotomy, the clinician proved to be correct 74% of the time, and the arthrogram accuracy in evaluating the medial meniscus was 89%; the majority of the errors were false positive diagnoses. In the 82 meniscus tears in which an arthrogram was performed the diagnosis was made in 80 cases, or 98%. The arthrogram accuracy in the lateral compartment was 81%; however, of the 31 lateral meniscus tears in which an arthrogram was performed, a positive diagnosis was yielded by arthrogram in only ten cases. In 34 lateral meniscus tears, a positive clinical diagnosis was made in only 12 cases. Arthroscopy was performed in 117 cases and proved helpful in patient management in 65 cases (55%). Arthroscopy was performed in 25 patients with lateral meniscus tears and a diagnosis of a lateral meniscus tear was made in all cases. The observations suggest that prior to performing an arthrotomy, arthroscopic examination of the knee should be performed routinely in patients suspected of having meniscus tears.

Adolescent↗
PubMed1980

Evaluation of the role of Histamine H1- and H2-receptors in cutaneous inflammation in the guinea-pig produced by histamine and mast cell degranulation.

1 The role of histamine H1- and H2-receptors in mediating the cutaneous inflammatory response produced by exogenous histamine and the release of endogenous histamine from mast cells has been investigated by a method which permits simultaneous, quantitative measurement of vasodilatation, vascular permeability and oedema formation. 2 Histamine and the selective H1-receptor agonist, 2-(2-aminoethyl) pyridine, both produced vasodilatation, increased vascular permeability and oedema formation whereas the selective H2-receptor agonist, dimaprit, produced only vasodilatation. 3 Mepyramine and cimetidine both reduced the vasodilatation response to histamine, the combination of antagonists being superior to either antagonist alone. Mepyramine (but not cimetidine) virtually abolished extravascular albumin accumulation and oedema formation. 4 Mepyramine and cimetidine both reduced the vasodilatation response produced by active cutaneous anaphylaxis and compound 48/80. However, mepyramine was less effective in reducing the vascular permeability response to mast cell degranulation than to histamine. 5 In conclusion, the vasodilator response to histamine is mediated by both H1- and H2-receptors; the permeability response to histamine is mediated solely by H1-receptors. A combination of H1- and H2-receptor antagonists appears to be more effective than either antagonist alone in reducing cutaneous inflammatory reactions involving histamine.

Animals↗
PubMed1979

Reduction of neglected congenital dislocation of the hip in children over the age of six years.

Thirty-two neglected congenital dislocations of the hip in twenty-two children over the age of six years were treated by traction, open reduction and Chiari osteotomy. In five hips, where prolonged traction failed to bring the femoral heads into the vicinity of the acetabulum, a shortening subtrochanteric osteotomy of the femur was performed. The overall results were good and this regime of treatment is recommended.

Child↗
PubMed1977

Tissue toxicity of antiseptic solutions. A study of rabbit articular and periarticular tissues.

The gross, histologic, and biochemical effects of four commercially available antiseptic solutions on rabbit knee articular and periarticular connective tissues were investigated. Rabbit knee joints were injected with 2.0 cc of either Betadine prep solution, Betadine scrub solution, pHisohex or 3% hexachlorophene. The opposite knees were injected with sterile saline. All animals were injected three times at 48-hour intervals and sacrificed 10 days after the last injection. The solutions containing detergents, Betadine scrub, and pHisohex caused severe gross and histologic damage to articular cartilage, synovia, and muscle. The hexachlorophene loss solution caused moderate histologic damage, but caused articular cartilage ground substance. Betadine prep solution caused only minimal gross and histologic damage, without any biochemical evidence of articular cartilage damage. If antiseptic solutions are to be used in irrigating or packing joint injuries, the use of Betadine prep is recommended.

Animals↗
PubMed1977

Surgical correction of congenital dislocation of the hip in children aged two to six years.

We report on a consecutive series of 68 children, between the ages of two and six years, with 97 neglected dislocated hips. The standard treatment consisted of traction, open reduction and innominate osteotomy. The results were satisfactory in most cases and the number of complications decreased significantly with improved surgical techniques. Additional operations, such as femoral varisation derotation osteotomy or Colonna arthroplasty, were performed only in exceptional cases for the treatment of complications. The treatment of neglected congenital dislocation of the hip after the patient has begun walking is a difficult orthopedic problem and and uniformly good results cannot be expected. Open reduction and innominate osteotomy appear to be the best form of treatment in the age group studied.

Child↗
PubMed1976

Lavage of septic joints in rabbits: effects of chondrolysis.

Septic joints were produced in rabbits which were then treated with systemic procaine penicillin. One group of animals also had surgical lavage at four and seven days after bacterial inoculation. In the infected joints there was a significant loss of hexosamine by five days and of collagen by nine days. Lavage delayed the loss of collagen.

Animals↗
PubMed1975

Compartmental evaluation of osteoarthritis of the knee. A comparative study of available diagnostic modalities.

The distribution and severity of osteoarthritis were investigated in 56 knees by history and physical examination, assessment of knee function, radiography with and without weight-bearing, double-contrast arthrography, and 99mTc-polyphosphate bone imaging. Compartmental involvement (medial, lateral, patellofemoral) was graded independently by 2 or 3 observers for each modality and was correlated with that observed during arthroscopy or direct surgical inspection. The more involved compartments were graded abnormal by all methods. In the less involved compartments, the gamma camera image was most sensitive to pathology, followed by arthrography. The choice of surgical technique and the prognosis depend upon accurate preoperative knowledge of the extent of disease.

Adult↗
PubMedDate not supplied

Investigations into the analysis of the rate of decay of the compound action potentials recorded from the rat sciatic nerve after death: significance for the prediction of the post-mortem period.

There have been a number of papers that have reported the investigations of electrical stimulation of muscle groups in order to determine the post-mortem period. To the authors knowledge, no techniques have been described that analyse the compound action potentials (CAP) of various nerve fibre groups after death. This paper reports the monitoring of both the amplitude and latency changes of the CAP recorded from a stimulated rat sciatic nerve after death. Initial results suggest that the method my be useful in determining the early post-mortem period within 1 or 2 h after death. It may also be of use in measuring nerve conduction delay in various pathological conditions that can affect the neural network; for example diabetes.

Action Potentials↗