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Biomedical subjects

D Dalela

Publications and source records attributed to D Dalela.

28 records · Page 2Linked to original sources

Routine radio-imaging in filarial chyluria--is it necessary in developing countries?

Chyluria is a common presentation of filariasis in developing countries and mostly affects economically poor classes. The judicious use of investigations is mandatory to keep the cost of treatment acceptable. A modified plan is suggested for managing such patients without using retrograde pyelography or lymphangiography. A total of 54 patients were studied at 2 separate institutions, with retrograde pyelography being carried out at one institution but not at the other. All patients were treated primarily by the instillation of 1% silver nitrate, with an initial success rate of 70%. Eight patients who failed to respond underwent pyelolymphatic disconnection, the success rate being 88%. The omission of retrograde pyelography and lymphangiography had no effect on either treatment or outcome. The value of these radio-imaging techniques is discussed.

Adult↗

Functional bladder neck obstruction in females--a revisit.

Functional bladder neck obstruction is supposed to be nonexistent or a very rare clinical disorder. In the past two and a half years, detailed synchronous, video pressure flow EMG studies were done in all the female patients who had evidence of obstructed voiding, poor flow and acute or chronic retention. The subjects of this study are nine females who had high sustained detrusor pressure, high opening pressure, low uroflow and silent sphincter during pressure-flow EMG study. A simultaneous urovideo recording showed either a closed bladder neck, inadequate funneling, intermittent or improper opening during voiding (when Pdet was high and sustained). These patients did not have any anatomical urethral obstruction, neurogenic disorder or systemic disease (like diabetes) affecting voiding. This stringent criteria of functional bladder neck obstruction was observed in nine patients. Five patients had acute or chronic retention and three patients had varying degree of renal failure. Initially all patients were managed by clean intermittent self catheterisation (CIC). Alpha blockers were empirically tried in six patients and had shown variable results. Bladder neck incision (BNI) was performed in two patients with rewarding success.

Adrenergic alpha-Antagonists↗

Prostate cancer: altering the natural history by dietary changes.

The importance of diet on the development and progression of prostate cancer was initially suggested by epidemiological studies. Since then, there has been a vast amount of research in this field. Compelling evidence now provides hope that evidence-based dietary alterations may markedly alter the natural history of this disease. Is there enough evidence for clinicians to be able to advise dietary modifications? The preliminary results no doubt are encouraging, but at present there seems to be no evidence to justify the widespread use of these proposed dietary interventions. However, as public awareness increases, all physicians involved with the care of patients with cancer of the prostate will need to be better armed with the current updates and advice on this issue.

Carotenoids↗