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Biomedical subjects

D D Petrunin

Publications and source records attributed to D D Petrunin.

At least 37 records · Page 2Linked to original sources
PubMed1984

[Immunochemical identification and physicochemical characteristics of human leukocytic beta 2-sialoglobulin (RAL-6)].

A new glycoprotein (RAL-6) was identified in human venous blood by immunochemical assay. During studies into the physicochemical properties, it was established that the glycoprotein has a mobility of beta 2-globulins and contains sialic acids. Study of RAL-6 content in tissue extracts from different organs of man and in biological fluids demonstrated the protein to be contained by pus extracts in a large quantity. The concentration of RAL-6 in hemolysates was found to be lowered in some of the diseases including those of the autoimmune nature.

Beta-Globulins↗
PubMed1982

[Immunochemical identification and physico-chemical characteristics of specific proteins of seminal plasma].

Two specific antigens of human spermatic plasma have been identified: thermostable alpha 1-globulin and alpha 2-microglobulin of fertility. The thermostable alpha 1-globulin presents a glycoprotein containing sialic acids with a molecular weight of 60000 +/- 7000. In addition to the sperm, it has been also identified in the saliva of men and women. Alpha 2-microglobulin of fertility is identical to placental alpha 2-microglobulin. This protein is specific for the reproductive system of men and women. The physicochemical properties of the test antigens are described.

Alpha-Globulins↗
PubMed1981

[Effect of specific placental proteins--trophoblastic beta 1-glycoprotein chorionic alpha 1-microglobulin--on the proliferation of lymphocytes and malignant fibroblasts in vitro].

A study was made of the action of trophoblastic beta 1-glycoprotein (TBG) and chorionic alpha 1-microglobulin (CAG1) on proliferation of malignant fibroblasts (transplanted L line) and on phytohemagglutinin-stimulated lymphocytes. TBG depressed proliferation of the stimulated lymphocytes and transformed fibroblasts (according to 3H-thymidine incorporation). A dose-response dependence was ascertained. CAG1 did not affect cell division. The inhibitory effect of TBG was seen to be reversed or decreased provided the lymphocyte culture was supplemented with CAG1. The decreased inhibitory effect of TBG in the presence of CAG1 was also noted in the L cell culture. It is likely that in vivo protection of intensely proliferating fetal tissues or tumor from the inhibitors is effected just in this way since placental proteins are synthesized both by embryonic and tumorous cells.

Alpha-Globulins↗
PubMed1981

[Evaluation of a trophoblastic beta-globulin preparation in the leukocyte adhesion inhibition test during pregnancy].

The leukocyte adhesion inhibition test was used to study the effect of trophoblastic beta-globulin preparations on the phase of fetal antigen recognition by sensitized lymphocytes from pregnant women. It was found that trophoblastic beta-globulin used in physiological concentrations does not exert an appreciable immunosuppressant effect on pregnant women's lymphocytes both in the first and third trimesters of pregnancy.

Beta-Globulins↗