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Biomedical subjects

D D Morehouse

Publications and source records attributed to D D Morehouse.

At least 37 records · Page 2Linked to original sources

The assessment of sphincteric activity in patients following trans-sphincteric urethral reconstruction.

12 patients who had previously undergone trans-sphincteric urethral reconstruction were studied with regard to their sphincter mechanisms. The method of study was by urethral pressure profile and urethral voluntary sphincteric pressure increment. This study showed that patients may undergo trans-sphincteric urethral reconstruction with preservation of normal profiles and voluntary pressure increases indicating preservation of the "external" sphincter mechanism.

Adult↗

Antilymphocyte globulin in renal transplantation: Nephrotic syndrome and infection as possible complications.

During a two-year period, nine patients received equine antilymphocyte globulin (ALG) as part of their immunosuppressive therapy following cadaver renal transplantation. Of these, three patients (33%) developed nephrotic syndrome. A fourth patient had proteinuria greater than 3 gm/24 hr not attributable to recurrent disease or rejection. Of 32 other patients with cadaver renal allografts done during the same time, none had nephrotic syndrome and two (6%) had proteinuria greater than 3 gm/24 hr, both with biopsy evidence of rejection. This suggests an association between ALG therapy and risk for developing nephrotic syndrome, but the mechanism is not clear and deserves further investigation. During the first three months following transplantation, the nine patients treated with ALG had 20 infections, which seems to be more per patient than in our other transplant recipients.

Adolescent↗