Biomedical subjects
Publications and source records attributed to D D Dykes.
A total of 206 paternity cases were tested for the erythrocyte enzyme esterase D (EsD) along with the 15 genetic marker systems routinely phenotyped. Of 39 observed exclusions of falsely accused males, 5 were exonerated by EsD. Reliability and ease of testing indicates that EsD is a useful exclusion determinant.
Pehnotypings of serum proteins and erythrocyte enzyme polymorphisms were used in addition to classic erythrocyte antigens in a study of 281 paternity cases. This group was compared with 877 cases in which only the erythrocyte antigens were tested. In the study group 80 exclusions were found for 52 alleged fathers. The expanded test battery increased the exclusion rate by 62%. In addition to 30 direct exclusions, serum proteins and erythrocyte enzymes corroborated indirect exclusions obtained with erythrocyte antigen tests in eight instances.