Search PubMed⌕ Search

Biomedical subjects

D D Daly

Publications and source records attributed to D D Daly.

At least 19 recordsLinked to original sources
PubMed1977

Early evoked potentials in patients with acoustic neuroma.

Using clicks with varying interstimulus intervals and coherent tone-bursts, early components of the auditory evoked potential (brain stem responses) were studied in four patients with confirmed acoustic neuroma. Abnormalities in responses appeared with shorter interstimulus intervals and with tone-bursts delivered monaurally to the involved ear; bilateral alterations occurred in one patient with brain stem displacement. The results indicate that BSR can provide a stable, independent, noninvasive measure of auditory nerve function useful in the early detection of acoustic neuroma. The results contribute to the understanding of the so-called human FFR.

Acoustic Stimulation↗
PubMed1976

Interlaboratory variability in determination of plasma antiepileptic drug concentrations.

The usefulness of plasma antiepileptic drug concentrations in treatment of epilepsy has been established, and many laboratories provide this service. A "blind" survey utilizing pooled patient plasma samples was conducted among 197 laboratories in the United States and Canada to establish the interlaboratory reproducibility. Three "patient specimens" containing different amounts of phenobarbital, phenytoin (diphenylhydantoin), primidone, and ethosuximide were employed; 112 laboratories reported results within five weeks. The average cost for analyzing four drugs in a single sample was $43.27. Half of the laboratories reported results outside +/- 1 standard deviation of the mean of five reference laboratories. Wide interlaboratory variability must be considered by the practicing physician. Until certified antiepileptic drug standards in a biologic matrix are available from the National Bureau of Standards, a volunteer quality control program among laboratories is needed.

Anticonvulsants↗
PubMed1975

Recovery of auditory function following meningitic deafness.

Two cases are presented that document improvement in hearing following Hemophilus influenzae meningitis. In both cases vestibular function was permanently lost. The possible anatomical and physiological sites of involvement are discussed. The two cases stress the importance of regularly scheduled audiometric reevaluations in cases of postmeningitic deafness.

Audiometry↗