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Biomedical subjects

D Cucinotta

Publications and source records attributed to D Cucinotta.

At least 145 records · Page 8Linked to original sources

Some laboratory aspects of hepatic tolerability of diftalone.

The hepatic tolerability of phthalazine-(2,2-b)-phthalazin-5,12-(7H,14H)-dione (diftalone--administered at the dosage of 750 mg/day p.o. for a mean period of 23 days--has been studied in 40 patients by means of: total plasma protein, albumin, fibrinogen, serum glutamin-oxalacetic transaminase, serum glutamic-pyruvic transaminase, lactic dehydrogenase, creatine phosphokinase, alkaline phosphatase, glycemic curve after glucagon and plasmatic elimination of bromosulphalein. A statistically but not clinically significant increase of the SGPT level is the only change observed.

Adult↗

[Bis-(hydroxy-2-ethylthyo)-1,10-decano in hyperlipaemic therapy (author's transl)].

The authors studied the effectiveness and biological tolerability of Tiadenol [Bis-(hydroxy-2-ethylthyo)-1,10-decano] against clofibrate, in a group of 38 hyperlipaemic (volunteers) subjects, with or without atherosclerotic disease. The results showed that the new hypolipidaemic drug has a great effect on cholesterolemia and trigliceridaemia, as does clofibrate. The statistic examination confirmed the results. This research didn't show any side-effects of the drug, which has a very good biological tolerability.

Adult↗