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Biomedical subjects

D Cosgrove

Publications and source records attributed to D Cosgrove.

69 records · Page 4Linked to original sources
PubMed1982

Complement components in kidney allograft recipients: relationship to cytomegalovirus infection.

Serum complement profiles of 19 renal transplant recipients were studied serially before and after renal transplantation to determine if there is any relationship between cytomegalovirus (CMV) infection and alteration in the serum complement (C) levels. Most patients had low serum C3 and C4 levels before transplantation, but afterwards these levels increased in some patients. Clq was elevated before and after transplantation. Factor B was low before transplantation, but after surgery, its level approached normal in patients without cytomegalovirus viremia, whereas in those with viremia, Factor B level became even more depressed. Circulating Factor B fragments were found in the sera of five out of seven patients with active cytomegalovirus infection, which suggests activation of the alternative pathway possibly related to active CMV infection.

Adult↗
PubMed1980

Association of immune responsiveness to cytomegalovirus infection with survival of renal allografts.

The association of immune responsiveness to cytomegalovirus infection was studied in relation to survival of renal allografts. The presence of anti-cytomegalovirus antibody in the pre-transplant patient was not associated with any detrimental effect on the graft survival. The presence or absence of cytomegalovirus antigen or of cytomegalovirus antibody, or later development of cytomegalovirus antibody, in no way affected the graft survival. The same conclusion was reached in cases when kidneys from male donors were used in cytomegalovirus antibody-postive patients.

Adult↗
PubMed1978

The radiological changes in infections of the spine and their diagnostic value.

This study describes the early radiological changes which occur in infections of the spine, by examination of the initial radiographs in 45 patients with proven spinal infection. The commonest radiological change in infection of the spine was a symmetrical lesion involving the adjacent surfaces of two vertebrae, with a variable degree of reduction in height of the disc space. A paravertebral abscess was a common associated finding. No radiological pattern was completely reliable in distinguishing tuberculous from non-tuberculous infections, but in white patients the formation of new bone strongly suggested a pyogenic lesion. The presence or absence of a paravertebral abscess was not helpful in distinguishing the variety of infection.

Adolescent↗
PubMed1976

Sedation in dentistry.

A philosophy for the use of sedation and anxiety control in everyday dental practice is described. The need for greater education in basic sedation techniques is emphasized.

Anesthesia, Dental↗
PubMedDate not supplied

Use of an intercostal vein for central venous access in home parenteral nutrition: a case report.

A key factor in the success of a home parenteral nutrition program is prolonged and safe access to the central venous system. There are some patients, however, in whom the cephalic, external jugular, internal jugular, subclavian, and saphenous veins cannot be used. In these patients, cannulation of an intercostal vein can be useful for central venous access. Such a patient was recently presented to our medical care facility with bilateral subclavian vein thrombosis, left external iliac vein thrombosis, and superior vena cava obstruction above the level of the azygous vein. A Broviac catheter was successfully introduced via a right intercostal vein cutdown with the catheter tip lying in the azygous arch. This is the first known description in an adult patient in the use of an intercostal vein to gain access into the central venous system.

Adult↗
PubMedDate not supplied

Cardiac rhythm and conduction disturbances in patients undergoing mitral valve surgery.

The occurrence and course of supraventricular rhythm and atrioventricular conduction disturbances were retrospectively compared in 206 patients with isolated mitral valve disease undergoing either valve replacement or ring annuloplasty (mitral repair) between January 1, 1985 and December 31, 1986. The replacement and repair groups were the same size and had approximately equal numbers of patients in sinus rhythm and atrial fibrillation preoperatively. The type of mitral valve operation did not affect the short-term outcome in terms of cardiac rhythm. For both groups, the incidence of patients crossing from sinus rhythm to atrial fibrillation and vice versa on the pre-discharge electrocardiography was equal, and both groups had a low incidence of clinically significant atrioventricular block.

Adult↗