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Biomedical subjects

D Conway

Publications and source records attributed to D Conway.

50 records · Page 3Linked to original sources
PubMed1987

Chlamydial and gonococcal antibodies in sera of infertile women with tubal obstruction.

Sera from 48 infertile women with tubal pathology and from 77 infertile women with normal fallopian tubes were tested by enzyme linked immunosorbent assay (ELISA) using Chlamydia trachomatis and Neisseria gonorrhoeae antigens. Control sera were obtained from women undergoing abortion, sterilisation, and from women practising barrier contraception. The results of ELISA for antibodies to chlamydiae were in close agreement with results published previously of an immunofluorescence test on these sera. Antibodies to C trachomatis were found in 73% of the infertile women with tubal pathology, significantly more than in any of the control groups. Only a very low prevalence (2-5%) of antibodies to gonococcal pili was found in all groups, except women undergoing abortion (16%).

Adult↗
PubMed1985

Cancer mortality in England in relation to levels of naturally occurring fluoride in water supplies.

Sixty-seven small areas in England have been classified into four groups according to the level of naturally occurring fluoride in their water supplies. Small area mortality statistics for 1969-73 have been used to look for differences in cancer mortality in relation to fluoride levels. Deaths from all cancers and from cancer at 12 specific body sites have been examined; no consistent trends in mortality are apparent. These results provide no evidence of a harmful effect of naturally occurring fluoride in water supplies.

England↗
PubMed1984

Chlamydial serology in fertile and infertile women.

Species-specific circulating antibodies to Chlamydia trachomatis were found in 75% of 48 infertile women with damaged fallopian tubes, 47.5% of 40 parous women seeking sterilisation, 46% of 63 women seeking termination of pregnancy, 31% of 75 infertile women with normal fallopian tubes, and 24% of 72 women using barrier contraception. High titres of antibody (greater than or equal to 1/1024) were found in 46%, 15%, 16%, 8%, and 7% of these groups, respectively, and were common in those women with a history of pelvic inflammatory disease or use of an intrauterine device. Thus, although the presence of antibody to C trachomatis was correlated with tubal damage, it was not diagnostic of tubal disease, since a substantial number of pregnant or potentially fertile women also had serological evidence of chlamydial infection. However, the results show that high titres of chlamydial antibodies in infertile women indicate the need for early laparoscopy to assess tubal status.

Adult↗
PubMed1983

Internal migration in contemporary Nepal: models which internalize development policies.

"A set of models is developed to assess at the interdistrict level the relative importance of economic, demographic, social and government policy determinants of internal migration in Nepal. The first 'proximate' model and the second 'structural' model estimates are generated using ordinary least squares regression and specification error is investigated by spatial autocorrelation tests of the residuals of each model in its reduced form....Finally, to formalize and evaluate empirically the linkages between the 'proximate' and 'structural' determinants, a simultaneous equation model is developed using three stage generalized least squares regression."

Asia↗
PubMed1981

Platinum-based combination chemotherapy in non-small cell lung carcinoma.

A series of 35 patients with advanced non-small cell lung cancer were treated with combination chemotherapy consisting of cis-diamminedichloro platinum (II), Adriamycin, 5-fluorouracil, methotrexate and vincristine. The objective response rate was 37.1% and the overall median survival 52.8 weeks. Notable toxicity was infrequent and reversible. Although the investigators have obtained higher response rates with other platinum-based combination chemotherapies, the present regimen appears superior in that other regimens fail to yield superior survival times while consistently inducing more severe toxicity.

Adult↗
PubMed1981

Surgical treatment of locally far-advanced lung carcinoma.

It has been our policy to employ radical lung resection as a primary treatment whenever possible in locally far-advanced lung cancer. In order to assess the therapeutic results, a total of 132 patients with locally far-advanced lung cancer who had radical lung resection were reviewed. Postoperative mortality was 10%. A significant difference in survival was seen between those patients receiving no adjuvant therapy, radiation or single agent chemotherapy and those receiving cis-platinum-based polychemotherapy and/or immunotherapy (respective median survivals 14.25 and 25.68 months, P less than 0.05 Breslow test or failure rats). Aggressive surgery followed by effective adjuvant therapy in locally far-advanced Stage III lung carcinoma appears to produce acceptable survival results.

Adenocarcinoma↗
PubMedDate not supplied

Emigration to North America: the continuing option for the Caribbean.

"A commonly held notion among Commonwealth Caribbean commentators on development prospects of the region, holds...that emigration options for the Caribbean are becoming more restrictive, and that traditional receiving countries such as Britain, the United States and Canada, have the will and purpose to restrict entry....Britain's effective immigration policies from 1962 to [the] present appear to amply demonstrate the situation, and exemplify a future restrictive international environment for future generations of Caribbean emigrant hopefuls seeking opportunities 'off the island' in traditional metropoles. This brief commentary argues the contrary."

Americas↗