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Biomedical subjects

D Chisholm

Publications and source records attributed to D Chisholm.

51 records · Page 3Linked to original sources
PubMed1975

Self-regulated methadone detoxification of heroin addicts. An improved technique in an inpatient setting.

We used a method of detoxifying heroin addicts involving a self-regulated schedule of methadone hydrochloride detoxification in an inpatient setting. This method allows the addict to receive methadone on an "as needed" basis within specified guidelines, thus permitting him to regulate his own detoxification. For this study, 30 chronic heroin addicts were detoxified using this self-regulated detoxification procedure. Measures of length of stay, amount of methadone required, and degree of patient satisfaction indicate that this is a practical means of withdrawing chronic heroin addicts that may have advantages over fixed withdrawal schedules.

Adult↗
PubMed1969

A comparison between the gastric and salivary concentration of iodide, pertechnetate, and bromide in man.

The concentration of iodide (I(-)) and pertechnetate (TcO(4) (-)) and bromide (Br(-)) has been measured simultaneously in gastric juice and parotid saliva. The combined gastric and salivary clearance for iodide and pertechnetate is more than twice the clearance of these ions by the thyroid gland. The concentration of the ions was in the order I(-)>TcO(4) (-)>Br(-) in both gastric juice and saliva. Differences exist between the secretion of iodide, pertechnetate, and bromide. Bromide, in contrast to iodide and pertechnetate, was found to be more concentrated in gastric juice than in saliva. The ratio of the iodide to pertechnetate clearance was greater in gastric juice than in saliva.

Adult↗
PubMedDate not supplied

[Use of quality of life measures in mental health economics and care planning].

Quality of life measurement is a key element in health economics and healthcare planning, particularly in chronic diseases associated to high morbidity and disability (i.e., mental disorders). This paper provides a critical review on the theoretical background of utility, on the methods for developing measures based on health preferences or values, and the composite indexes derived from them (DALY and QALY). Then the practical use in mental health is revised both in burden of disease studies and cost-utility analysis. There is an important requirement on the part of mental health researchers and policy makers alike to pay close attention to the underlying methods and construction of utility-based estimates of health outcome.

Costs and Cost Analysis↗