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Biomedical subjects

D Chatzoulis

Publications and source records attributed to D Chatzoulis.

4 recordsLinked to original sources

How do tears drain? Technetium studies.

We examined the tear drainage system of twenty-fiv normal volunteers by scintillography with Technetium Tc 99m (Pertechnetate). We photographed the changes occurring in the lacrimal sac and nasolacrimal duct during closure and opening of the eyelids. Our findings support Jones' views of normal tear drainage. The tracer was concentrated in the lacrimal sac while the lids were closed for 3 minutes and descended into the nasolacrimal duct as soon as they opened.

Eyelids

Extraocular observations in episcleral sponge implants.

The follow-up of 262 cases of retinal detachment operated on after the Custodis-Lincoff method in combination with cryopexy permitted the following observations: (1) The implant protruded in a number of cases under an intact conjunctiva and Tenon's capsule without discomfort to the patient. This protrusion depended mainly on the size and the manner of fixation of the implant, the distance of the point of fixation from the limbus and the condition of the conjunctiva. (2) Changes were observed in the conjunctiva in the fixation area, such as subconjunctival haemorrhage, cystoid degeneration of the conjunctiva and rupture with extrusion of the sponge. Subconjunctival haemorrhages were observed in 3.4% of the cases and were either absorbed or led to an inflammation. Cystoid degenerations occurred in 2.2% of our cases. These were limited to the edge of the sponge proximate to the limbus and involved only cases of radial fixation. Rupture of the conjuctiva and extrusion were noticed in 3.4% of the cases. (3) An inflammation due to the sponge was observed in 4.1% of the cases. Its time of onset varied between 3 days and 22 months. According to the time of onset the patients were divided into three groups. The gravity of the inflammation was proportionate to the earliness of the time of onset. Predisposing factors for the above complications were mentioned and discussed.

Conjunctiva

[Intraocular complications following Custodis-Lincoff operation].

This investigation is based on 262 cases of retinal detachment treated with episcleral silastic sponge implants and cryopexy. Anatomical restoration of the retina after one operation or more was successful in 89 percent. Drainage of subretinal fluid was carried out in 52 percent of the cases. Supplementary light-coagulation 3 or 4 weeks after the operation was applied in 43 cases (17 percent) in order to seal off retinal holes on the buckle due to inadequate chorioretinal adhesion following cryopexy. Insufficient adhesion was directly related to the retinal elevation in the area of the tear. Chorioretinal haemorrhages in the group without release of subretinal fluid were caused by the following factors: Repeated cryo-application in the same place, application of the probe on the open part of the tear instead of around the tear, sponge-fixation in the immediate area to vortex veins, pressure exerted by the sponge on choroidal and retinal vessels, particularly in persons of advanced age. Local haze of the vitreous corresponding to the location of the cryp-application was directly related to the number of applications and the position of the tear. Vitreous haze was more frequent where the hole was situated towards the ciliary body. Pigment migration was observed in 9 percent of the cases. It should be noted that this complication was also encountered preoperatively in a group amounting to 4 percent of the total number of cases after padding of the eyes and absorption of subretinal fluid. Such cases should be distinguished from those of postoperative occurrence of pigment migration. Detachment of the choroid happened more often in the group in which subretinal fluid was released. In this group expulsive haemorrhage also occurred, which, apart from the choroidal detachment, resulted, immediately upon drainage of subretinal fluid, in high intracular pressure. Macular puckering was noticed in 5 cases (2,7 percent). In 4 out of the 5 cases with this complication, the tear was located towards the posterior pole and sponge fixation was radial.

Choroid