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Biomedical subjects

D Charles

Publications and source records attributed to D Charles.

150 records · Page 9Linked to original sources
PubMedDate not supplied

[The heart and malaria].

The authors study cardiac symptoms in malaria and consider four different situations. -Cardiac symptoms in 50 cases of acute malaria: these symptoms are functional in 14 p. 100 of the cases and objective in 40 p. 100 of the cases. Changes of repolarisation of the ECG recorded in 36 p. 100 of the cases may be related to hyperthermia (acting as a stress test) or to a malarial change in myocardium. - Cardiac symptoms in other malarial aspects: they are caused by a myocardiopathy resulting of malarial chronic anemia. - Cardiac symptoms during malarial fit in patients already affected by a cardiopathy: they are mainly blood hypopressure, persistent tachycardia and they are more a consequence of the hyperthermic strain applied to an already damaged heart than of malaria by itself. - Cardiac symptoms, related to the use of antimalarial drugs. They are obvious in acute voluntary intoxications, in excessive doses or in case of normal doses in patients with renal insufficiency or hypokaliemia.

Adolescent↗
PubMedDate not supplied

[Staphylococcal septicemias in Algiers (report of 14 cases) (author's transl)].

Staphyococcal septicemia is rare (0.19 p. 100 of admittances). The origin of this kind of infection could be located in all cases out of the sanitary units, and in 12 out of the 14 cases, patients under 30 years old were concerned. The main disorders were in pulmonary tract, kidneys and heart. A fatal issue occured 6 times due in most cases to a delayed admittance. A good study of sensitivity to antibiotics and a treatment associating several antibiotics are necessary.

Adult↗
PubMedDate not supplied

[Pathophysiology of drepanocytemia (author's transl)].

The mutational molecular processes are reminded with recent advances in the understanding of the sickling phenomenon and the pathogenesy of the thrombotic complications. New therapeutic prospects are considered.

Anemia, Sickle Cell↗
PubMedDate not supplied

[Pathogenesis of chronic hemolysis in drepanocytemia (author's transl)].

Frequently chronic hemolysis is not obvious in drepanocytemia and must be looked for with proper technics. Its origin lies chiefly in the corpuscular process of sickling but extra-corpuscular factors must be considered, and among them the role of spleen seems prevailing.

Anemia, Sickle Cell↗