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D Cassi

Publications and source records attributed to D Cassi.

13 recordsLinked to original sources

n--> infinity limit of O(n) ferromagnetic models on graphs

Thirty years ago, H. E. Stanley showed that an O(n) spin model on a lattice tends to a spherical model as n-->infinity. This means that at any temperature the corresponding free energies coincide. This fundamental result is no longer valid on more general discrete structures lacking in translation invariance, i.e., on graphs. However, only the singular parts of the free energies determine the critical behavior of the two statistical models. Here we show that for ferromagnetic models such singular parts still coincide even on graphs in the thermodynamic limit. This implies that the critical exponents of O(n) models on graphs for n-->infinity tend to the spherical ones and depend only on the graph spectral dimension.

Journal Article↗

Increased plasma level of vascular endothelial glycoprotein thrombomodulin as an early indicator of endothelial damage in bone marrow transplantation.

We investigated the nature of hemostatic alterations occurring after bone marrow transplantation. In 45 patients, we evaluated the coagulation parameters, naturally occurring anticoagulants and thrombomodulin at days +15 and +22 after conditioning therapy. It was observed that endothelial cell damage is a central pathogenetic mechanism in some BMT complications. The increased plasma level of thrombomodulin after conditioning therapy is therefore discussed as a marker of endothelial cell injury. At day +15 a significant increase of fibrinogen from 276.1 mg/dI to 389.1 mg/dI was observed, while the natural anticoagulants all decreased significantly. Eleven patients with clinical complications related to endothelial damage had a significant thrombomodulin increase which, in uncomplicated patients, remained unchanged or resulted in lower than baseline values. Analysis of the data shows a strong correlation between clinical findings, reflecting endothelial cell injury and thrombomodulin increase when the increment is > or = 30%. We found a significant elevation in thrombomodulin in 70% of clinical complications related to endothelial cell damage namely: septicemia, GVHD, VOD. There were four cases (or 9%) of false positive data, and only two (or 4.5%) of false negative results. We therefore propose thrombomodulin assessment as a valid parameter to monitor chemotherapy toxicity-related complications.

Adolescent↗