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Biomedical subjects

D Carrasco

Publications and source records attributed to D Carrasco.

64 records · Page 4Linked to original sources

Reduction of postherpetic neuralgia in herpes zoster.

BACKGROUND: Persons 50 years of age and older are not only at increased risk of developing herpes zoster, they are also more likely to suffer the long-term morbidity of postherpetic neuralgia (PHN). PHN is pain persisting after the rash of herpes zoster has healed. PHN affects at least 40% of all herpes zoster patients over age 50 and over 75% of herpes zoster patients over age 75; PHN is the single most common neurologic condition in elderly patients. OBJECTIVE: The objective of this review is to evaluate interventions that may reduce or even eliminate PHN. No single therapy has been consistently effective for PHN. The most effective approach appears to be with the use of antiviral therapy early in the course of herpes zoster. The goals of ongoing studies in herpes zoster are to develop interventions that will further reduce the symptoms of PHN and/or to eliminate PHN by prophylaxis using the varicella vaccine. CONCLUSIONS: Reduction of PHN can best be achieved with the use of antiviral medication early in the course of herpes zoster; other classes of drugs are minimally effective in treating established PHN. Widespread use of the varicella vaccine may lead to secondary reductions in PHN in the distant future.

2-Aminopurine↗

Macrodactyly: report of eight cases and review of the literature.

Congenital enlargement of one or several digits of the hands or feet (macrodactyly) is a rare disorder. A considerable proportion of the patients with this condition are referred to dermatology departments. The majority of the cases reported in the literature represent hamartomas with combined hypertrophy of several, predominantly lipomatous, soft tissue components and overgrowth of bone. The differential diagnosis includes Klippel-Trenaunay-Weber syndrome, neurofibromatosis, Milroy disease, and Proteus syndrome. We describe eight cases of congenital macrodactyly, discuss the findings, and propose a simple clinicopathologic terminology.

Adolescent↗

[Focal nodular hyperplasia of the liver: benign lesion with often surgical treatment. Magnetic resonance and laparoscopic findings].

The diagnosis of benign hepatic tumor lesions is every day more frequent. Three cases of focal nodular hyperplasia (FNH) accidently detected during the performance of echography and/or CAT for other reasons are presented. The difficulty or diagnostic doubts which the different imaging techniques may present before these findings, together with the relatively young age of these patients may lead to the adoption of a surgical attitude in lesions of a clearly benign character. The role of magnetic resonance (MR) as a non invasive diagnostic technique in this type of disease is of note.

Adult↗