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Biomedical subjects

D C Whitaker

Publications and source records attributed to D C Whitaker.

At least 55 records · Page 3Linked to original sources
PubMed1989

Microcystic adnexal carcinoma with mandibular invasion and bone marrow replacement.

A 51-year-old man with microcystic adnexal carcinoma of the face is reported. In addition to extensive soft tissue invasion by the cancer, there was direct bone invasion into the marrow of the mandible as well as perineural spread along the mental and inferior alveolar nerves. This represents the first case of microcystic adnexal carcinoma with documented bone invasion. Recognition of the aggressive nature of this cancer with potential for invasion into the skull is important for proper evaluation and treatment.

Bone Marrow↗
PubMed1989

Cancer of the cheek.

The combined skills of the micrographic surgeon and the head and neck surgeon offer excellent cure rates and reconstructive techniques for primary cutaneous tumors of the cheek. In most instances, structures crucial to facial function and appearance can be preserved or rehabilitated. This interspecialty approach to such tumors results in the best care for the patient and a high sense of professional satisfaction for the surgical team.

Cheek↗
PubMed1988

Periocular basal cell carcinoma in adults 35 years of age and younger.

Thirteen young adults (ages 21 to 35 years) with periocular basal cell carcinoma were identified out of 409 patients of all ages with basal cell carcinoma (3.2%). Factors related to patient and tumor characteristics were analyzed. Two groups of patients were identified. Most of the patients tended to be of light complexion and eye coloring without a family history of basal cell carcinoma. A second group of patients with basal cell nevus syndrome was identified. The tumors generally were single small lesions, but not nodular, usually being morpheaform in tissue structure. The tumors were present for an average of 4.3 years before diagnosis. The area of excision was 5.4 times the clinically measured size.

Adult↗
PubMed1988

Basal cell carcinoma arising in a sebaceous nevus during childhood.

It is uncommon for malignancy to develop in a sebaceous nevus before puberty. We report a case of basal cell carcinoma arising in a sebaceous nevus during childhood in a normal-appearing lesion. Periodic evaluation to detect malignant degeneration is recommended for children even if removal is encouraged at a future date.

Age Factors↗
PubMed1988

An approach to patient assessment and preparation in cutaneous oncology.

An outline of the many phases of preoperative evaluation of the dermatologic surgery patient is presented. Special emphasis is given to patient assessment and to patient preparation. The purpose of this review is not to create a compendium of steps that one must slavishly perform before each surgical procedure. Instead, it represents an effort to emphasize the importance of adequate preoperative evaluation and to discuss some of the subtleties that may be overlooked by the dermatologic surgeon.

Humans↗
PubMed1988

Wound infection rate in dermatologic surgery.

Most dermatologic surgery is performed in clinical settings and not in the rigorous sterile environment of a hospital operating room. This prospective study measures the wound infection rate over a 2 1/2 year period for cutaneous surgery performed in a clinical environment. This percent infection rate compares very favorably with that of formal operating room settings.

Dermatologic Surgical Procedures↗
PubMed1988

Management considerations for cutaneous neurophilic tumors.

The proper management of patients with neurophilic skin cancers is often quite difficult. When present, neurophilic invasion significantly worsens the prognosis. Important considerations for managing patients with cutaneous neurophilic tumors and illustrative cases are presented.

Aged↗
PubMed1988

Lateral nose and perinasal defects: options in management following Mohs micrographic surgery for cutaneous carcinoma.

Primary and recurrent cutaneous carcinomas of the nose and the adjacent perinasal tissues often invade more deeply than cutaneous carcinomas in other areas. The operative defect may be large. The physician who has to close these defects is faced with a challenging problem that requires an appreciation of facial anatomy and function. There is often more than one option in the repair of these defects. Important concepts in the management of lateral nose and perinasal surgical defects are discussed.

Humans↗
PubMed1988

Carbon dioxide laser matricectomy.

We have performed a total of 13 matricectomies in 9 patients utilizing the carbon dioxide laser. To date, there have been no complications and minimal morbidity from this technique. With follow-up ranging from 8 to 24 months, no patient has experienced regrowth of nail at the treated site. In conclusion, we believe that carbon dioxide laser ablation is an effective technique for performing nail matricectomy.

Adolescent↗
PubMed1988

Postoperative techniques for corneal protection in Mohs micrographic surgery.

Corneal abrasion or injury can complicate periorbital surgery. In micrographic surgery of the eyelids and canthal regions, enough palpebral tissue may be sacrificed so that corneal exposure and injury can occur. In the interim between surgery and reconstruction, adequate measures must be taken to ensure protection of the globe. Techniques that protect the corneal epithelium for small or large surgical defects are described.

Corneal Diseases↗
PubMed1987

Recurrent and residual sebaceous carcinoma after Mohs' excision of the primary lesion.

We reviewed the histories of three patients with sebaceous carcinoma (two of the eyelid and one of the caruncle) who had had their tumors excised by surgeons experienced in the Mohs' technique. In each patient the tumor was considered totally excised. In one patient, residual intraepithelial pagetoid sebaceous carcinoma of the eyelid was detected incidentally when a reparative flap was placed. In the other two patients, invasive sebaceous carcinoma recurred, necessitating orbital exenteration; one patient has regional lymph node metastases. Because of the difficulty in detecting pagetoid spread on frozen sections and the multicentric nature of sebaceous carcinoma, we advocate managing these tumors by wide local excision, checking margins with high-quality permanent sections.

Adenocarcinoma↗
PubMed1987

Microscopically proven cure of actinic cheilitis by CO2 laser.

Actinic cheilitis is a premalignant condition of the lip frequently seen in individuals with chronic sun exposure. Various surgical and ablative therapies have been employed, but microscopic outcome has not been well documented. In this study CO2 laser ablation was performed on 16 patients with actinic cheilitis that involved 50% or greater of the lower lip. Pre- and post-treatment biopsies were performed to assess results of therapy. After treatment all 16 patients showed microscopic clearing of atypical cells and disorderly maturation characteristic of actinic cheilitis. One patient had clinical recurrence at 14 months, which was retreated with laser.

Aged↗
PubMed1987

Mohs surgery report: an approach to cutaneous surgical defects of forehead and eyebrow following Mohs micrographic surgery.

Elective excisions of the forehead are relatively easy to plan because of the prominence of horizontal skin folds and vertical glabellar furrows. However, the variety of defects in that region which result from Mohs micrographic surgery for cutaneous tumors frequently present reconstructive challenges. Principles applicable to this anatomic region and illustrative cases are presented and discussed.

Cicatrix↗
PubMed1986

Lymphangioma circumscriptum following mastectomy and radiation therapy.

We describe a woman who developed clear, tense vesicles in an area of chronic lymphedema 8 years following mastectomy and radiation therapy. The vesicles showed the clinical and pathologic features of lymphangioma circumscriptum, which can develop as a late sequelae of the lymphatic damage inherent in some forms of cancer therapy.

Breast Neoplasms↗
PubMed1982

Laser surgery in the medically compromised patient.

Dermatology has entered a new dimension with the introduction of the laser. There are expanding clinical indications for laser excision. The CO2 laser in the cutting mode can incise tissue as sharply as finely honed steel, yet its photocoagulative properties allow rapid sealing of blood vessels and lymphatics. The physician can thereby perform in a relatively bloodless surgical field. Minimal adjacent normal tissue is injured, there is less local postoperative edema, and fewer postoperative analgesics are required. Since there is no need to use epinephrine as a local vasoconstrictive agent and there is no need to use electrocoagulation for control of hemorrhage, CO2 laser excision presents less risk to the medically compromised patient. The CO2 laser may also diminish the risk of seeding or spreading neoplastic cells in the perioperative field.

Aged↗