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Biomedical subjects

D C Sharma

Publications and source records attributed to D C Sharma.

At least 19 recordsLinked to original sources
PubMed1997

Effect of silver leaf on circulating lipids and cardiac and hepatic enzymes.

About 50 mg of silver leaf (metallic silver) was given daily by mouth to 30 healthy volunteers for 20 days. A statistically significant hypophospholipidemic, hypotriglyceridemic, hypocholesterolemic and hypoglycemic effect was observed. This was accompanied by a less marked fall in total lipids and significant rise in HDL-cholesterol. In addition, a decrease in plasma enzymes - alkaline phosphatase (ALP), glutamate oxaloacetate transaminase (GOT), glutamate pyruvate transaminase (GPT), creatine phosphokinase (CPK), gamma glutamyl transpeptidase (GGT) and lactate dehydrogenase (LDH) was noted. This was statistically significant for all enzymes except CPK. The safety of ingested silver foil is indicated by absence of pathology in urine and unaltered levels of protein and albumin in the plasma. These observations suggest that silver could be beneficial in conditions like diabetes mellitus, obesity and atherosclerosis.

Female↗
PubMed1996

Chromium uptake and toxicity effects on growth and metabolic activities in wheat, Triticum aestivum L. cv. UP 2003.

Chromium (Cr) at graded levels when added in sand culture of wheat (T. aestivum L. cv. UP2003) under glasshouse conditions resulted in reduction in biomass, chlorophyll and activities of catalase and peroxidase while enhanced acid phosphatase and ribonuclease activities. Elevated levels of Cr supply significantly reduced the concentration of inorganic phosphorus. With an increase in Cr supply the uptake of chromium also increased significantly in different plant parts especially in roots. Above metabolic lesions due to Cr in wheat provided evidence that the element in nutrient medium if present in excess may be inhibitory to plant growth and development.

Biomass↗
PubMed1995

Correction of anemia and iron deficiency in vegetarians by administration of ascorbic acid.

Twenty-eight strict vegetarians were given 500 mg ascorbic acid twice daily after lunch and dinner for two months. Hemoglobin and certain iron status parameters were measured before and after the treatment. Ascorbate treatment increased mean hemoglobin by 8%, serum iron by 17% and transferrin saturation by 23% and decreased total iron binding capacity by 7%. All these changes were statistically significant. The rise in serum ferritin was 12%. The serum protein or copper level did not indicate their dietary deficiency, while initial serum ascorbate level were low which rose by 60% on therapy. It is concluded that ascorbate supplementation is a better method of improving hematologic and iron status than iron salt administration.

Adolescent↗
PubMed1991

The changing pattern of maternal and neonatal anemia at Udaipur during 2 decades in relation to poverty, parity, prematurity and vegetarianism.

The analysis of blood of 50 nonanaemic (Hb greater than 10 g%) and 50 anaemic (Hb less than 10 g%) mothers and of their cords with regard to haemoglobin, iron, iron binding capacity and percent saturation of iron was done. It was found that (A) the severity of anaemia and iron deficiency was much greater in women belonging to poor class, vegetarian families or multigravida, (B) the children born prematurely or to anaemic mothers, poor families, strict vegetarians or multiparous women were at a greater risk of developing anaemia and/or iron deficiency, (C) the severity of anaemia and iron deficiency has decreased in last 2 decades in the population served by Zanana Hospital, Udaipur, (D) vegetarianism may be one of the important causative factor of anaemia in pregnant women of this region and their newborn children, and (E) the incidence of macrocytic or macrocytic hypochromic anaemia in pregnant women has become rare in last 20 years.

Anemia↗
PubMed1991

Iniencephaly with cyclopis (a case report).

Iniencephaly is a rare neural tube defect. We report a rare association of iniencephaly with cyclopia, probably the third such report in the literature.

Abnormalities, Severe Teratoid↗
PubMed1988

An investigation into the role of ascorbic acid in renal calculogenesis in albino rats.

Neither stone nor calcium oxalate crystal deposition was observed in the kidneys of rats after oral ingestion of 60 mg. L-ascorbic acid daily for three months, although urinary excretion of stone inhibitors (magnesium and citrate) was decreased and oxalate increased. The highly acidic pH of urine and reduced calcium excretion might have prevented their deposition.

Animals↗