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Biomedical subjects

D C Carter

Publications and source records attributed to D C Carter.

At least 217 records · Page 12Linked to original sources
PubMed1972

Insulin infusion test of gastric acid secretion.

In view of the disadvantages of the standard insulin test for completeness of vagotomy a continuous insulin infusion test has been developed. Twenty-six tests were carried out on 12 healthy male volunteers. A dose of 0.04 unit of soluble insulin/kg/hr was found to produce the highest acid secretion with the least severity of symptoms of hypoglycaemia. The pattern of response was a plateau of acid secretion and of hypoglycaemia, and repeated studies in six subjects showed that the results were reproducible. Evaluation of this test after vagotomy and comparison with the standard insulin test are now required.

Adult↗
PubMed1972

The effect of vagotomy on gastric adaptation.

Gastric adaptation was impaired immediately after the performance of complete vagotomy in a series of 20 acute experiments in the dog. Preliminary isolation of the intact vagi in 10 of these animals produced alterations in adaptation similar to those seen after vagal division. It is concluded that alterations in gastric adaptation are not a reliable intraoperative aid to complete vagotomy. These findings may be significant in the interpretation of all intraoperative tests for vagotomy.

Adaptation, Physiological↗