Search PubMed⌕ Search

Biomedical subjects

D C Campbell

Publications and source records attributed to D C Campbell.

At least 37 records · Page 2Linked to original sources
PubMed1990

Thermoablation treatment for trichiasis using the argon laser.

This paper presents a brief review of the literature regarding current treatment modalities for trichiasis and their complications. The technique of Argon laser thermoablation of lashes is described. A total of 12 patients with recurrent trichiasis involving 15 eyelids were treated and the procedure was found to be effective in 12 eyelids (80%). The follow-up period was three to six months. The laser settings used were Argon blue-green wavelength, spot size 50 to 100 microns, exposure time 0.05 to 0.10 seconds and power 1200 to 2000 mW. Advantages of the technique were precise application and selectivity, lack of complications, non-requirement for infiltrative anaesthesia and ease of performance. Disadvantages were the need for up to three treatments in some patients and the technique only being suitable for treating small numbers (up to six) of lashes.

Aged↗
PubMed1988

Fractures of the polyethylene bearing insert in Bateman bipolar hip prostheses.

Six cases of fractures of the polyethylene bearing insert of Bateman bipolar hip prostheses were observed in three patients at four to eight years after implantation. Three fractured prostheses were salvaged by replacement with new bearing inserts. In three patients, excessive acetabular cartilage wear was the indication for revision to total hip arthroplasty. Although dislocation and component disassembly have been reported as complications of the Bateman and other bipolar prostheses, fractures of the polyethylene bearing insert seems not to have been previously reported. The presumed mechanism of failure is cyclic loading of a femoral cup that is tipped into varus alignment. This concentrates stress on the weakest part of the polyethylene insert--the deep circumferential groove that joins the leaflets to the main body of the insert. Obesity and overuse were associated factors in this rare complication.

Adult↗
PubMed1986

Immunological abnormalities in asymptomatic homosexual men: correlation with antibody to HTLV-III and sequential changes over two years.

A prospective study on 100 homosexual male volunteers was designed to examine immunological function in relation to sexual activity and infection with the human T cell lymphotropic virus Type III (HTLV-III). Complete data were available for 71 men. In a comparison with 100 age-matched heterosexual men, the study group of 100 men had a significantly higher mean serum IgG level (12.1 +/- SD 2.7 g/l vs. 10.9 +/- 2.4 g/l, p less than 0.01) and a significantly lower mean number of CD4 (T4) cells (845 +/- 310 X 10(-6)/l vs. 1128 +/- 375; p less than 0.01). For the study group, seropositivity for anti-HTLV-III was present initially in 22 per cent and was associated with a higher mean level of serum IgG and lower mean number of CD4 cells. Among seropositive homosexual men a low CD4/8 ratio was attributable to low numbers of CD4 cells in those without lymphadenopathy and to high numbers of CD8 cells in those with lymphadenopathy. For the seronegative homosexual men, a low CD4/8 ratio as a result of an increased CD8 cell count was present in 12 of 60, and was associated with numerous sexual partners and semen culture positive for cytomegalovirus. In two seropositive subjects a low CD4/8 ratio due to a decrease in the CD4 cell count was predictive of the development of AIDS by some two years. For the 71 men with complete data over two years, indices of cell-mediated immunity, including mean counts of CD4 cells, the CD4/8 ratio, and score for recall of cutaneous delayed type hypersensitivity increased during the first year but not during the second year in both seropositive and seronegative subjects. These increases occurred in association with changes in sexual practices and activity, but could not be attributed to any one particular factor.

AIDS-Related Complex↗
PubMed1985

Children's burns due to cresol.

A total of 213 burns were admitted to the Burns Unit at the Royal Children's Hospital, Brisbane, during the 2 year period 1982-1983. Of these 118 were due to scalds and 33 were due to flame burns. However, one patient was admitted following burning with cresol after inhalation. We have had several such injuries in previous years. Two such patients are discussed and the problems of cresol burns are briefly discussed. Such injuries pose a problem inasmuch as while not frequent, they are injuries that could probably be prevented.

Burns, Chemical↗
PubMed1985

A quantitative automated immunoassay for fibrinogen/fibrin degradation products.

We describe a prototype quantitative automated assay for fibrin and fibrinogen degradation products, a particle-enhanced turbidimetric inhibition immunoassay (PETINIA) in the Du Pont aca discrete clinical analyzer. This assay involves a latex particle reagent with covalently bound fibrinogen and a polyclonal antiserum raised in rabbits against human fibrinogen. A special secondary sample-collection tube quantitatively removes fibrinogen from citrated plasma and inhibits further fibrinolysis, independent of heparin concentration. The assay range is 0-100 mg/L, in fibrinogen equivalents. The CV for the assay is less than 10% when performed with the aca. Nonclottable fibrin and fibrinogen fragments are measured by the assay, the greatest sensitivity being directed at the E domain of the fibrinogen molecule. We illustrate with case studies the potential of this assay for providing clinical information not obtainable with currently available qualitative and semi-quantitative assays.

Adult↗
PubMed1979

Mechanical cornpicker hand injuries.

The mechanical cornpicker causes tearing anse injuries from 1962 to 1975 were studied with regard to mechanism and extent ohe time of injury in 36% of hands, and in 73% of the remainder following treatmophylaxis, and antibiotics, and 73% hands required some form of delayed surgical treatment. Antibiotics did not appear to be helpful. Eighty-nine ps the most common cause given for farmers for their injuries. Excluding four pr permanently disabled patients, the average length of disability was 135 days. Eighty-nine per cent of patients experienced some permanent impairment of hand function. The mechanical cornpicker is described, and the importance of its proper use and physician's emphasis on accident prevention as well as treatment are stressed.

Adolescent↗
PubMed1979

Evaluation of the Gambro Lundia Major 1.36 m2 disposable parallel plate dialyzer.

The Gambro Lundia Major 1.36 m2 dialyzer was assessed in vivo in ten hemodialysis patients. Urea and creatinine clearances (measured as whole blood values at 60 minutes with a blood flow rate of 200 ml/minute) were 166 +/- 8 m/minute (mean +/- standard error of the mean, n = 9) and 115 +/- 4 ml/minute (n = 11). The creatinine clearance is 15% lower than in vitro data. There was a marked decrease in urea and creatinine clearance with third use of the dialyzer. The ultrafiltration rate was 490 ml/hour/100 mmHg. The priming volume was 125 ml (at a transmembrane pressure of 100 mmHg) and residual blood volume in the dialyzer was 0.57 +/- 0.11 ml (n = 5). The handling, storage and ease of disposal of the dialyzer is better than previous models and its performance characteristics are clinically acceptable.

Adult↗
PubMed1979

Total joint arthroplasty. The hip.

Total hip arthroplasty, one of the most successful orthopedic procedures of this century, can provide relief of pain and improved function in a wide variety of hip conditions. Long-term follow-up has shown, however, that problems can occur, especially with the femoral prosthesis. As a result of this, surface-replacement total hip arthroplasty was developed, and at present it appears to be a very useful procedure for younger patients with concentric hip disease. Both procedures are discussed along with restrictions and complications inherent in their use.

Arthroplasty↗
PubMed1979

Role of surgery in the management of pulmonary sporotrichosis.

Management of four patients with sporotrichosis is summarized; one was treated medically and three were treated surgically. Thirty-seven cases from the literature are reviewed. The role of surgery in the management of pulmonary sporotrichosis is outlined as follows: (1) diagnosis of pulmonary infiltrates and/or pulmonary cavities of undetermined origin, (2) surgical intervention in patients with persistent infiltrates with cavitary lesions resulting from sporotrichosis, following failed medical treatment, and (3) resection of associated pulmonary cavitary lesions in patients in spite of adequte medical control of sporotrichosis. Surgical principles that must be observed in the management of pulmonary sporotrichosis follows:(1) Resection is the procedure of choice. The magnitude ranges from segmental resection to pneumonectomy. Clean resection is necessary. (2) Antifungal drug therapy--preferably with amphotericin B--is advisable preoperatively and postoperatively, since the major cause of late death is progression of the disease when clean resection has not been feasible. (3) Resection combined with drug therapy can be curative without increased risk in physiologically operable and anatomically resectable disease. (4) Thoracoplasty can be a lifesaving procedure for bilateral cavitary lesions with severe hemoptysis in patients with impaired pulmonary functions.

Adult↗
PubMed1976

Recovery from unilateral visuo-spatial neglect?

Patients who had demonstrated unilateral visuo-spatial neglect on a simple drawing and copying task three to four weeks after a right hemisphere stroke were reassessed five months later. Although the incidence of neglect as defined had dropped markedly in that period, they remained impaired on tests of spatial analysis and visual perception relative to a group of right hemisphere patients without neglect. The measurement of neglect is discussed in the light of both these results and the stability of the neglect group's abnormal position preference on one of the tests administered.

Cerebrovascular Disorders↗