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Biomedical subjects

D Bordoş

Publications and source records attributed to D Bordoş.

14 recordsLinked to original sources
PubMedDate not supplied

[Experimental model of heterotopic renal transplantation in rat].

This study describes the experience with a new technique for heterotopic kidney transplantation in the laboratory rat. This technique combines already known aspects in renal experimental transplantation, with technical improvements added to each surgical step. Ten heterotopic kidney transplantation were performed. Immediate postoperative survival was 100% and at 48 hours was 90%. The patency of the vascular anastomosis checked at 72 hours in survivors was 100%. As a preliminary study, 20 renal hilum dissections were done, noting the topographical aspects of the renal vessels. Representing a standardized and easy to use model, this solid organ transplantation technique is a valuable tool for studying the immunological and physiopathological aspects of transplantation and for refining the microsurgical skills.

Animals↗
PubMedDate not supplied

[Difficult laparoscopic cholecystectomy].

From 2505 cases operated between 1994-2000, the authors selected a lot of 889 cases of difficult cholecystectomy, which after classical criteria would have been classified as contraindications of laparoscopic procedure. This study analyzed of intraoperative incidents, the conversion rate and particularities of operative tactics and techniques. The lot of patients includes 889 cases of difficult laparoscopic cholecystectomy. The patients were selected according to classical contraindications of laparoscopic cholecystectomy: obesity, liver cirrhosis, previous operated abdomen, severe cardio-pulmonary diseases, ages over 70 years, acute cholecistitis. The rate of intraoperative incidents and accidents was 19.9% (177 cases), in comparison to intraoperative incidents and accidents rate in "easy" laparoscopic chole-cystectomy which was 15.5% (251 cases from 1616 patients). The conversion rate in case of difficult laparoscopic cholecystectomy was 6.1% (55 patients) and 3.2% in the lot of "easy" cholecystectomy. The postoperative morbidity was 6.4% (57 patients) and 5.5% (147 patients) in the lot of "easy cholecystectomy. The postoperative mortality was 0.6% (6 deaths) and 0.3% (5 deaths) in the lot of "easy" cholecystectomy. In this paper are discussed the modalities and the technical particularities of a difficult laparoscopic cholecystectomy, able to lowering the risk of operative incidents and postoperative complications. In conclusion, laparoscopic cholecystectomy can be safely performed to the majority of patients with lithiasic cholecistitis, by an experienced surgical team.

Adult↗
PubMedDate not supplied

[Percutaneous treatment of the liver hydatid cysts under sonographic guidance].

This paper is a retrospective study of the first 51 cases of liver hydatid cysts, which underwent a conservative treatment between April 1996-December 2000. There were 28 females and 23 males with a mean age of 40.1 years (7-65), which had 63 liver hydatid cysts. In the right liver lobe were located 46 cysts, in the left liver lobe were located 7 cysts and in 10 cases cysts were located in both liver lobes. In 4 cases a pulmonary hydatidosis was associated. Abdominal ultrasound and CT scan were routinely performed and the cysts were classified in type I and II after Gharbi's classification. All of these 63 cysts were treated by ultrasound guided fine-needle percutaneous puncture with aspiration and instillation of sterile alcohol 95 degrees. Pre and postoperative the patients were treated with mebendazol or albendazol. They were followed-up by ultrasound and CT scan examination in the second day postoperative and monthly. No new cysts were noted during an average follow-up of 14.7 months and maximal cyst diameter decreased with minimum 72%. Two episodes of reversible anaphylaxis were encountered. The mean hospital stay was 3.3 days. In this paper the indications for conservative treatment and preliminary results of this method are discussed.

Adolescent↗
PubMedDate not supplied

[Experimental model of orthotopic uterus transplantation in the laboratory rat].

This study develops and standardizes an experimental model of uterus transplantation in the laboratory rat. Twelve orthotropic uterus transplantation were done. Animals were randomized in three groups. Postoperative survival was 100% and 75% at 72 hours. Recipients were euthanased at 24 hours, 48 hours and 72 hours and the grafts were harvested. Patency of the microsurgical anastomoses was 100% at 24 hours, 63% at 48 hours and 0% at 72 hours. The explanted uterine grafts were fixed in formalize and analyzed under light microscopy. The acute allograft rejection starts during the second day after transplantation. In additional dissection, anatomy of the pelvic region with regard to the topography of the uterus, tube and ovarian vessels was studied. This model of uterus transplantation in rats proposes a standardized tool for further research regarding cellular mechanisms of the acute allograft rejection and, for future, pregnancy of the transplanted uterus.

Animals↗
PubMedDate not supplied

[Surgical treatment of thyroid nodules. The immediate results after different thyroidectomy methods].

The extension of the resection for thyroid nodules depends both on nodules' nature and immediate or late postoperative complications risks. This clinical study analyzed the immediate complications appeared after partial thyroidectomy comparatively with those developed after total thyroidectomy. We studied 1411 patients operated in two clinics (from Romania and from France) which have two different attitudes concerning the width of the resection. Paralysis of recurrent laryngeal nerve occurred in 1.0% of patients with partial thyroidectomy and 3.0% of patients with total thyroidectomy, while only one patient (0.6%) developed permanent hypoparathyroidism after total thyroidectomy. In conclusion, total thyroidectomy can be performed by experimented surgeons with a recurrent or parathyroid injury risk similar to partial thyroidectomy. However, the surgeon should take into account the patient survey capacity and the discomfort produced by life substitutive treatment.

Adenocarcinoma, Follicular↗
PubMedDate not supplied

[Thyroid radiography and thyroid lymphography].

A detailed representation is made of the technique used in the performance of thyroidography and an analysis is carried out of the authors' personal experience Thyroidography and thyroido-limphography have been applied in 40 patients with various diseases of the thyroid gland. The authors evaluate the method as being simple to perform, accessible, well tolerated and capable to provide significant morphological data (size of the lobes, the presence of retrosternal thyroid tissue, structure of the gland), also allowing for visualization of the cervical limph-nodes.

Adolescent↗
PubMedDate not supplied

[When to prescribe scintigraphy in the exploration of thyroid nodules?].

Scintigraphy is employed almost systematically in current medical practice for initial thyroid nodules investigation. More and more authors observed that scintigraphy has lost importance confronted with others modern exam, but there are no statistical essay to demonstrate this fact. The aim of our work was to study, on 369 patients, the real contribution of scintigraphy to establish diagnosis and therapeutical strategy. Scintigraphy was truly useful only in 47 (12.7%) patients. We may conclude that thyroid scintigraphy ought to be indicated only in low TSH thyroid nodules, ectopic goiter and, eventually, in metastasis uptake radioactive iodine.

Humans↗
PubMedDate not supplied

[Reconstruction of cervical esophagus by using laparoscopically assisted jejunal loop harvesting and microsurgical transfer].

For segmental cervical esophageal reconstruction, the free transfer of jejunal flap tends to become a standard procedure. Graft harvesting by laparotomy presumes increased morbidity at donor area level. There was described by now in the literature laparoscopic techniques for harvesting of jejunal graft, which have reduced the complications following laparotomy. We wish to present here an experimental model of laparoscopically assisted harvesting of jejunal flap used for reconstruction of cervical esophagus by free transfer. The harvesting of jejunal segment was achieved in 12 dogs; 4 cases subsequently underwent microsurgical free transfer. There are presented original contributions of authors. The harvesting average time was 115 minutes; the meantime graft ischaemia was 48 minutes in 4 cases with microsurgical transfer. Postoperative survival was 100%. Graft viability was achieved in 75% at 12 hours and 50% at 24 hours. No major operative accidents were recorded. We present a standardized experimental model, which could be an usefull guide in human therapeutics.

Animals↗
PubMedDate not supplied

[Therapy of lithiasis of the main biliary passages].

On the basis of a total of 3692 surgical interventions performed on biliary pathways, of which 431 (11,6%) for lithiasis of the hepato-choledocus, the authors discuss the indications, the limitations and the results of surgical treatment in this affection. The postoperative death rate was 10,3% in the first 10 years of the period during which these interventions have been performed and decreased to 5,5% in the last 10 years. The late results were good and very good in 85% of the cases. In view of the continuing decrease in the death rate after surgery, and for improving late results, the authors stress the necessity of early interventions in the lithiasis of main biliary pathways. They also stress the correct exploration of the hepato-choledocus in the course of all surgical intervention upon the biliary pathways.

Adolescent↗
PubMedDate not supplied

[Treatment of hernias and eventrations with alloplastic material (Mersilene type mesh)].

Between 1973 and 1979 the authors have performed 126 interventions, as follows: 27 hernias (18 of the inguinal type and 9 umbilical ones), and 99 eventration. They used alloplastic materials for consolidation or substitution of the musculo-aponevrotic wall of mediocre quality. In practice the "Mersilene" alloplastic material was used, made of dacron fibers, which provides a series of advantages: good tolerance, efficient sterilisation without undergoing degradation, possibility for use in reparation of large wall defects, high resistance. The net was applied for consolidation purposes in most of the cases (111 in all), and was placed either above the aponevrosis, or pre- or intra-peritoneally. In 15 patients it was used for substitution, when eventration resulted in a large muscular-aponevrotic defect. The results were very good, and a single recidive was noted, as well as two partial rejections, that did not however result in recidives.

Adult↗