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Biomedical subjects

D Bonvalet

Publications and source records attributed to D Bonvalet.

At least 55 records · Page 3Linked to original sources

[Reappearance of soft chancre: comments on the current epidemic in Paris (author's transl)].

A total of 678 cases of soft chancre were treated in one hospital between 1973 and 1979. The majority of the patients were males (97 p. cent), and most of them came originally from Maghreb or Black Africa. Contamination was from prostitution (61 p. cent) or chance acquaintances (29 p. cent). The genital ulceration was often clinically atypical, frequently syphiloid; pain was present in only 59 p. cent of cases, and adenopathy, noted in 63 p. cent of patients, had the appearance of an inflammatory bubo in only 23 p. cent. The present high frequency of soft chancres, and their misleading clinical characteristics, makes it sometimes difficult to establish the clinical differential diagnosis from syphilitic chancre, but confirmation of the latter is supplied by direct examination and culture to search for Ducreys bacillus, this being indispensable for establishing the correct diagnosis. Treatment with sulfamethoxazole trimethopin or streptomycin prevents complications and cures the affection in one or two weeks.

Adolescent↗

[Histopathology of lymphomes (author's transl)].

This histologic classification is based upon the arrangement and cytologic composition of the infiltrate. We separate diseases with intraepidermal exocytosis from diseases without intraepidermal exocytosis. In the first group, mycosis fungoides is the most important: the infiltrate is often polymorphous, but sometimes it consists of histiocytes and lymphocytes. Varying number of Sézary cells are present. The Woringer-Kolopp syndrome and histiocytosis X are included in this group as well. The second group comprises many neoplastic diseases: mycosis fungoides without Pautrier microabscesses, so-called 'reticulosis', 'Crosti's reticulosis', leukemia and lymph node lymphoma. Difficulties may arise in the differential diagnosis between these various diseases with well-differentiated lymphocytes and without intraepidermal exocytosis. These diseases must also be differentiated from the non-malignant lymphocytic infiltrates found in lupus erythematosus, lymphocytoma cutis and Jessner's lymphocytic infiltration of the skin.

Dermatitis, Exfoliative↗

[The difference forms of "parapsoriasis en plaques". A report of 90 cases (author's transl)].

The term parapsoriasis was used by Brocq (1902) to group a number of conditions previously described under different names. This group has since then been modified, the same conditions being described under separate names and these have led to a great confusion especially between countries. In this study of 90 cases, three types of parapsoriasis en plaques are distinguished. The "parapsoriasis digitiforme" (40 cases) or benign type, or xanthoerythrodermia perstans, or chronic superficial dermatitis is characterized by small, oval or finger-like, yellow or pink patches. The histology is frequently not characteristic, but in a few cases, there is an exocytosis localized "en flammèches" in the epidermis. The condition is usually permanent but none of these cases has progressed to mycosis fongoides. The parapsoriasis "en grandes plaques simples" (25 cases) is characterized by few pink patches (3 to 5), larger than in benign type. In our cases the transformation to poikiloderma atrophicans vasculare is not observed. One of these cases progressed to mycosis fongoides. The "parapsoriasis en grandes plaques poïkilodermiques" (25 cas), or poikiloderma atrophicans vasculare, prereticulotic poikiloderma, atrophic parapsoriasis, parapsoriasis lichenoides, is characterized by large patches, in limited number, showing a reticulated pigmentation and slight atrophy with telangiectasia. Five cases changed into mycosis fongoides and 4 cases showed some symptoms of malignancy; The histologic features are the same in the two last types: sometimes they are non-specific, in numerous cases the picture is characteristic with micro-abscesses or "flammèches"; in some cases there is a dense infiltrate with a clearly defined lower limit: this histologic appearance can be seen in cases without transformation into mycosis fongoides.

Adult↗

[Follicular tumidus retro-auricular lichen planus (author's transl)].

Referring to three comparable cases, a new form of lichen planus is described. This form is characterized by a prominent lesion, violaceus in color or pigmented, with white yellowish specks mimicking milia. The histologic picture of lichen follicularis, the presence of typical papules of lichen distant from the retro-auricular lesion make it possible to consider this clinical aspect as a variety of lichen planus.

Adult↗