[Generalities on vascular lesions in collagen diseases].
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Biomedical subjects
Publications and source records attributed to D Bontoux.
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The authors report a case of Yersinia enterocolitica rheumatism which presented atrial arrhythmias similar to those seen in atrial disease, but which resolved after 3 weeks and have not recurred over the subsequent 38 months. This case adds to the list of the cardiac manifestations of yersiniosis and raises the problem of acute forms of auricular disease.
In a patient suffering from rheumatoid arthritis thorough investigations led to the discovery of complete deficiency in the 7th component of the complement. A study of the patient's family tree confirmed the hereditary, codominant autosomal character of the deficiency, unrelated to the HLA system. The complement-dependent serum functions were investigated: the opsonizing and chemotactic activities were preserved, but bactericidal properties were lacking. Coagulation studies showed disorders in platelet aggregation in the presence of thrombin, and these were corrected by the addition of C7. The association of a dysimmune disease with C7 deficiency is probably not fortuitous; it might result from a common gene abnormality or, in some cases, from repeated infections.