Biomedical subjects
D Bone
Publications and source records attributed to D Bone.
Left ventricular volumes with ventricular inhibited and atrial triggered ventricular pacing.
Left ventricular (LV) volumes were assessed with equilibrium radionuclide angiocardiography at rest and during exercise in nine patients with high-degree AV block treated with ventricular inhibited (VVI), which was subsequently changed to atrial triggered ventricular pacing (VAT). The ventricular rates were similar at rest but higher on exercise during treatment with VAT (102 ppm) than with VVI (71 bpm). The LV end-diastolic volume tended to be larger with VAT than with VVI pacing, both at rest (185 vs. 145 ml) and during exercise (220 vs. 162 ml). The LV end-systolic volume also tended to be larger at rest (110 vs. 81 ml) and during exercise (149 vs. 83 ml). The LV ejection fractions were similar at rest but on exercise they decreased to significantly lower levels with VAT (0.35), while remaining unchanged with VVI (0.47). One mechanism for this difference could be an enhanced contractile state in VVI pacing compared with VAT pacing.
Treatment of feline cryptococcosis with ketoconazole.
Explore the source record for details and available documents.
Thallium-201 scintigraphy after acute myocardial infarction.
Fifty-five patients with acute myocardial infarction were examined with thallium-201 scintigraphy before discharge from hospital. Fifty-one showed significant scintigraphic defects. The number of abnormal Q waves in a 12-lead ECG but not the maximal ASAT value for each patient were correlated to the total estimated image defect. Mortality during the follow-up period of 14-28 months was not related to the estimated total image defect, but the two early deaths occurred among patients with the most dilated left ventricles.
Differentiation of pulmonary embolism from chronic airways obstruction by a dual isotope technique.
Explore the source record for details and available documents.
A non-invasive test of gastric function.
Using 98Tcm a non-invasive test of gastric function has been developed which completely obviates the need for a nasogastric tube and which adds to the accuracy of existing tests by overcoming losses due to incomplete aspiration or gastric emptying. 99Tcm is handled by the stomach like Cl-, the gastric secretion of which is equal to that of H+. The value of the pentagastrin stimulation test in the presence of varied gastric pathology is discussed in relation to 50 patients. Other possible diagnostic uses of the test are evaluated and a method of carrying out an insulin test by a modification of the technique is described.
Cytomegalovirus infections in human renal transplants.
Explore the source record for details and available documents.
Polar presentation of coronary angiography and thallium-201 single photon emission computed tomography. A method for comparing anatomic and pathologic findings in coronary angiography with isotope distribution in thallium-201 myocardial SPECT.
Individual results of coronary angiography were compared with tomographic myocardial scintigraphy (SPECT) in 99 patients. Coronary angiography findings were transferred to polar maps. Borders between arteries were assigned angles in a coordinate system constructed as a compass-rose. Areas perfused by different arteries were described by sectors. Findings were visually compared with the perfusion defects in a polar presentation of thallium-201 SPECT also described by angles. The mean values and SD for the angles representing arterial borders and perfusion defects were presented. The left ventricular myocardium was perfused by 3 coronary arteries in 92/99 patients. Dominant left artery was present in 7/99 patients; 79 perfusion defects were related to 118 arterial sectors 84 per cent had totally or partially matched stenotic arteries. Inter-individual differences in distribution of coronary arteries influence the localization of perfusion defects in myocardial SPECT and can be estimated with this polar presentation method.