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Biomedical subjects

D Boghen

Publications and source records attributed to D Boghen.

36 records · Page 2Linked to original sources

Primary aberrant third nerve regeneration.

The clinical and neuroradiological features in 4 patients with the syndrome of aberrant regeneration of the third nerve are presented. In contrast to what is commonly seen, the syndrome was not preceded by third nerve palsy. A petrous apex-cavernous sinus meningioma was the underlying lesion in all 4 patients. Surgical and pathological confirmation of the diagnosis was obtained in 3. Regardless of whether the other ocular motor nerves are spared (as in our patients) or involved (as in other cases reported in the literature), primary aberrant regeneration of the oculomotor nerve appears to be characteristic of a cavernous sinus meningioma.

Adult↗

Myoclonus in familial restless legs syndrome.

Eighteen members of a family were affected over a span of five generations with the restless legs syndrome, transmitted as an autosomal dominant trait. Ten patients had myoclonus. The propositus, a 57-year-old man, suffered from repeated, intense, asymmetric flexion jerks of the lower extremities, alternating with fidgeting and friction movements of the legs; all occurred at night prior to sleep and severely interfering with it. The patient's movements ceased with the onset of stage 1 sleep, while in his brother, the motor activity persisted in stages 1 and 2 of sleep.

Humans↗

She could not look to either side.

A young woman presented with the recent onset of an inability to move the eyes on a horizontal plane. Examination revealed limited horizontal gaze to the right and a complete left ophthalmoplegia. The limitation of eye movement could not be overcome by the doll's head maneuver. Other signs included bilateral orbicularis oculi weakness and brisk deep tendon reflexes. Her condition gradually improved and two months following the onset of the illness she was symptom free.

Acute Disease↗