An improved method for the determination of urinary dimethyl phosphate.
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Animals↗
Biomedical subjects
D Blair
Publications and source records attributed to D Blair.
A new family of Monostome flukes (Platyhelminths, Digenea) from the dugong, Dugong dugon (Müller).
The family Labicolidae is erected to contain a new species of Monostome fluke occurring in abcesses in the upper lip of the dugong from northern Australia. Labicola elongata is described as a new species and figured.
Abscess↗
Macropotrema, pertinax gen. et sp. nov. (Digenea: Paramphistomidae) from a wallaby, Macropus agilis, in northern Australia, and associated pathology.
Macropotrema pertinax gen. et sp. nov. (Digenea: Paramphistomidae) is described from the caecum of the macropodid marsupial Macropus agilis (Gould, 1842) from northern Australia. The new genus is characterised as follows: ventro-terminal acetabulum bearing many papillae; oral sucker with constriction and paired diverticula; oesophagus with muscular bulb; cirrus sac and genital sucker absent; testes symmetrical, unlobed, preovarian; Laurer's canal opening anterior to excretory pore. The genus is placed in the subfamily Pseudodiscinae Näsmark, 1937. At the point where the worm attaches to the caecal wall of the host, the entire mucosa is destroyed and there is an inflammatory cell infiltration in the intact mucosa surrounding the attachment site.
Animals↗
Emerging and reemerging helminthiases and the public health of China.
Despite great strides in their control throughout the People's Republic of China, helminth infections remain an important public health problem. The Institute of Parasitic Diseases of the Chinese Academy of Preventive Medicine, under the guidance of the Chinese Ministry of Health, completed a nationwide survey of more than 1 million people that showed the high prevalence and intensity of intestinal nematode infections; prevalence can sometimes exceed 50% in the Yangtze River valley provinces. Schistosoma japonicum is also a major cause of illness in this region. Attempts to control Chinese helminthic diseases with conventional anthelminthic drugs have been partially thwarted by high posttreatment rates of reinfection. Recently, several new human trematode pathogens have been identified. Novel approaches to chemoprophylaxis and vaccination may alleviate the public health problem caused by Chinese helminths. However, recombinant helminth vaccine development will depend on first cataloguing the extensive genetic diversity of Chinese helminths and candidate vaccine antigens. Evidence from biogeography, genetics, and systematics suggests that the genetic diversification of Chinese helminths and their vectors is an ongoing evolutionary process that began 12 million years ago near the convergence of major Asian river systems. Construction of the Three Gorges Super Dam on the Yangtze River may promote the emergence and reemergence of new helminths and their snail vectors
Animals↗
Schistosome dermatitis in North Queensland.
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Australia↗
[A new recipient cell line for transfection of biologically active oncogenes].
The properties of the new immortalized rat cell line (REF-1) were analyzed. These cells can be used as recipient ones in transfection assays. REF-1 cells never convert spontaneously to transformed phenotype during long-term passages in vitro unlike NIH3T3 cells. This peculiarity allowed to use REF-1 cells for identification of oncogenes, which induce slow-growing tumors. The following oncogenes were used in gene transfection experiments in order to test their effects: activated human EJ-ras; N-ras; v-myc; v-mos; activated tpr-met and c-hu-met. REF-1 cells, transfected with the members of ras family; v-mos and tpr-met were found to be transformed in vitro and induce tumors in nude mice, on the contrary of c-hu-met- and v-myc-transfected cells, which are non-tumorogenic. A number of clonal cell lines carrying different oncogenes were obtained. The detailed analyses of integration and expression of exogenous sequences of different oncogenes has been presented in 18 clonal cell lines.
Animals↗
Indosolenorchis hirudinaceus Crusz, 1951 (Platyhelminthes; Digenea) from the Dugong, Dugong dugon (Müller) (Mammalia; Sirenia).
Indosolenorchis hirudinaceus Crusz, 1951 from the caecum and large intestine of the dugong (Dugong dugon Müller) is redescribed from specimens from the Red Sea, East Africa, Sri Lanka, Japan, Indonesia and Australasia. Specimens described by Dollfus (1950) as Zygocotyle species are referred to Indosolenorchis hirudinaceus. There is some doubt concerning the identity of the genus Solenorchis as described by Hilmy (1949), but for the time being, it seems best to retain Solenorchis and Indosolenorchis as separate genera.
Animals↗