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Biomedical subjects

D Blair

Publications and source records attributed to D Blair.

At least 109 records · Page 6Linked to original sources
PubMed1981

A test of interlingual interaction in comprehension by bilinguals.

This study tested bilingual subjects' interaction of knowledge of both languages in comprehension. Spanish-English bilinguals and English monolinguals heard 36 sentences, all spoken in English. Twelve were normal English sentences, 12 contained Spanish word order, and 12 contained word-for-word translations of Spanish idioms. The dependent measures was performance on a phoneme-monitoring task; subjects pressed a button when they heard a particular phoneme within each sentence. Immediately following each sentence, subjects wrote down as much of that sentence as they could recall. Results showed that bilingual subjects pressed the button equally quickly for all sentences, but monolinguals were faster for control sentences than for idiom-translations, which was interpreted to mean that a knowledge of Spanish helped the bilinguals in processing the test items semantically.

Humans↗
PubMed1978

Analysis for salicylic acid in serum by high-performance liquid chromatography.

We report a specific and sensitive quantitative assay for salicylate in serum or plasma. As little as 3 microliter of sample can be analyzed by an external standard procedure and larger volumes by diluting with the internal standard (o-methoxybenzoic acid). No extraction or derivatization is necessary and salicylic acid and the internal standard elute in 6 and 3.75 min, respectively. Peak-height ratios are linearly related to concentrations between 10 and 500 mg/liter. By comparison with an existing fluorometric method, our procedure is faster, more specific, and more sensitive.

Aspirin↗
PubMed1977

Acetaminophen in serum and plasma estimated by high-pressure liquid chromatography: a micro-scale method.

We describe a capillary-sampling method for serum or plasma acetaminophen by cation-exchange chromatography. As little as 1.5 mul of plasma or serum and an equal volume of the internal standard (N-butyryl-p-aminophenol) were run, with a precision of +/- 5% between duplicates. Acetaminophen and the internal standard chromatographed in 32 and 50 min, respectively, distinct from intrinsic plasma peaks and peaks caused by other medications.

Acetaminophen↗
PubMed1976

Dichlorvos -- a 2-year inhalation carcinogenesis study in rats.

To determine the effects of dichlorvos vapour on the tumour incidence in rats, 5 week old Carworth Farm E strain rats weighing between 94 and 150 g were exposed to 0, 0.05, 0.5 and 5.0 mg/m3 in a 2-year inhalation study. The growth rate of all treated rats was depressed, particularly in the males. There was increased survival of the rats exposed to 5 mg/m3. There were no consistent differences in food intakes, organ weights, haematological or blood chemistry estimations, except in cholinesterase activites, amongst the various groups of rats. No compound-related differences were seen in acetylcholine and choline estimations carried out on a small number of female rats' brain tissues after two years' exposure. There were no gross or microscopical compound-related changes in the rats' tissues. Ultrastructural examination of the respiratory tissues of the rats from the control and 5 mg/m3 group showed no changes attributable to dichlorvos. The results of a relative risk analysis of the tumour data showed that no dose-related increase in tumour risk was established for rats of either sex. These data confirm the results of earlier st.udies supporting the safety of insecticidal uses of dichlorvos.

Animals↗
PubMed1976

Observations on the life-cycle of the strigeoid trematode, Apatemon (Apatemon) gracilis (Rudolphi, 1819) Szidat, 1928.

The life-cycle of Apatemon (A.) gracilis was completed in the laboratory. The snail host is Lymnaea peregra (Muller). The cercaria is redescribed from a wide range of material. Metacercariae were found in naturally infected rainbow trout (Salmo gairdneri Richardson), three-spined sticklebacks (Gasterosteus aculeatus L.) and stone loach (Nemacheilus barbatulus (L.)) from Scotland and in three-spined sticklebacks from Iceland. In trout, most metacercariae were found in the pericardial cavity, in sticklebacks, the eye, and in loach, the body cavity. In infection experiments, cercariae from naturally infected Scottish snails developed in three-spined sticklebacks, rainbow trout and brown trout (Salmo trutta L.). Under experimental conditions cercariae did not penetrate stone loach, although this species is naturally infected with A. gracilis. The phenomenon of fish host specificity is briefly discussed. Development of the metacercaria is described. Excystation of metacercarial cysts with pepsin and trypsin solutions is unlike that reported for any other digenean; the contents of the cyst appear to be under pressure. In pepsin, layers of the cyst wall peel back from one end. When transferred to trypsin, one pole of the cyst ruptures and the worm is forcibly expelled.

Animals↗