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Biomedical subjects

D Bhargava

Publications and source records attributed to D Bhargava.

16 recordsLinked to original sources
PubMed2001

Tonsillar actinomycosis: a clinicopathological study.

Actinomycosis has been known to involve virtually every anatomic site in the body. Although actinomycosis has been identified in resected tonsils, its possible role in adeno-tonsillar disease has received little attention. A clinicopathological study of 302 patients who had adeno-tonsillar surgery is presented. Tonsillar actinomycosis was present in 86 (28.5%) patients. The statistical analysis revealed a significant association (P<0.0001) of actinomycosis and tonsillar hypertrophy (56.8%) compared to only 10.3% in the recurrent tonsillitis group. A statistically significant association (P<0.0001) of tonsillar actinomycosis and sickle cell anaemia, beta thalassaemia, bronchial asthma and beta haemolytic streptococcal infections was also seen. This data supports a predisposition of the above conditions to tonsillar actinomycosis and adeno-tonsillar hypertrophy and a possible etiopathologic role of this organism in adeno-tonsillar hypertrophy and disease. Although the clinical association of actinomycosis and tonsillar hypertrophy and beta haemolytic streptococcal infection has been described before the association of actinomycosis with sickle cell anaemia, beta thalassaemia and bronchial asthma is being observed for the first time in literature.

Actinomyces↗
PubMed2001

Palatal presentation of scleroma.

A case with palatal presentation of scleroma is presented due to its rarity and unusual manifestations. The patient presented with only palatal symptoms. Nasal endoscopy revealed signs of all three stages of scleroma: catarrhal, granulomatous and sclerotic stages. Histopathology was vital in the diagnosis. The patient was treated by medical therapy, and palatal symptoms were relieved by uvulopalatopharyngoplasty.

Adolescent↗
PubMed2001

Endoscopic sinus surgery for orbital subperiosteal abscess secondary to sinusitis.

Subperiosteal orbital abscess (SPA) is a serious complication of paranasal sinusitis, which can lead to blindness or even death. A quick response is necessary as this condition is treatable. Early surgical intervention is indicated if there is risk of visual loss, or if no improvement is observed within 48 hours of starting medical therapy. Three patients with orbital SPA secondary to sinusitis treated successfully by Functional Endoscopic Sinus Surgery (FESS) are presented in this case series. The surgical indications were impending visual loss with an abscess and cellulitis impinging on the optic nerve in one child and in the other two patients, a lack of clinical response within 48 hours after starting systemic antibiotic. CT scans, nasal endoscopy, and ophthalmologic examinations are mandatory during the evaluation process. The advantages of FESS in these patients were the avoidance of external ethmoidectomy and its external facial scar, an early drainage of the affected sinuses, SPA, and the eradication of the disease from the fronto-ethmoidal region leading to an enhanced recovery and a reduced hospital stay. FESS is also a safe, convenient and minimally invasive procedure in patients presenting with serious complications of sinusitis.

Abscess↗
PubMed1999

Carabid beetle invasion of the ear in Oman.

Two cases of human ear invasion by a predaceous beetle, Crasydactylus punctatus Guerin (Coleoptera; Carabidae), are reported from the Sultanate of Oman. The first case was that of a 35-year old woman who suffered a severe otologic injury caused by the biting and chewing of the external auditory canal and the tympanic membrane. The beetle then entered the middle ear and caused sensorineural hearing loss. The second case involved a 22-year-old male from whose ear a specimen of the same species was successfully removed after it was immobilized with 10% lidocaine spray. These cases are presented with discussion.

Adult↗
PubMed1997

Chondroid syringoma of the nose: report of a case.

Chondroid syringoma or mixed tumour of the skin is a rare benign tumour which can present on the face. We present here the case of a patient who underwent an excisional biopsy of a small painless nodule in the soft triangle of the nose for cosmetic reasons. The clinical presentation, histology and treatment, with review of the relevant literature, is discussed.

Adenoma, Pleomorphic↗
PubMed1996

Anisakiasis of the tonsils.

A six-year-old Indian girl presenting with clinical features of chronic recurrent tonsillitis, had a tonsillectomy. Histopathology revealed a cross-section of an Anisakis worm in the tonsil. This report documents a new location in the human host for this rare parasite.

Anisakiasis↗
PubMed1996

Heterotopia of the tonsil.

The histopathological finding of heterotopias or choristoma is rare. This paper describes two patients who presented with chronic recurrent tonsillitis and underwent tonsillectomy. Histological examination revealed heterotopic cartilage in the tonsil of one patient and bone in that of the other.

Adult↗
PubMed1977

Carcinoembryonic antigen in colonic lavage.

Colonoscopic lavage was performed for assay of carcinoembryonic antigen (CEA) concentration in patients with small and large colonic adenomas, in patients with adenocarcinoma of the colon, and in normal controls. CEA concentration was considerably higher in colonoscopic lavage as compared to plasma. CEA concentration in normal controls and in patients with colonic adenomas less than 1 cm in size were not significantly different. CEA concentrations in patients with colonic adenomas greater than 1 cm in size and in patients with adenocarcinoma of the colon were significantly higher than those observed in patients with small adenomas and in the normal controls. In all except 2 patients, plasma CEA concentrations were normal. Assay of CEA concentrations in colonic lavage may have potential application in the further assessment of the mucosa at risk for colon adenomas and for colon cancer. It does not appear to be accurate enough for diagnosis of colon cancer in individual patients.

Adenocarcinoma↗