[Metastasis of breast carcinoma to the intestinal tract and endometrium].
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Biomedical subjects
Publications and source records attributed to D Beyer.
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Reported in this paper is experience obtained since 1978 from surgical removal of the tracheal bifurcation in combination with pneumonectomy in 38 cases. Squamous cell carcinoma centrally growing from the upper lobe was recorded from 24 patients to whom 36 interventions had been applied for bronchial carcinoma. 50 per cent of all operations in conjunction with pneumonectomy were performed on patients in the pT3NOMO stage. The cumulated 3-year survival rate amounted to 37 per cent. Mortality in hospital accounted for 18.4 per cent and was thus clearly higher than what had been recordable from standard techniques in carcinoma surgery. Causes of postoperative deaths included insufficient sutures in three cases, pulmonary embolism in 2, and pneumonia in the contralateral residual lung in another 2. Standardised surgical and anaesthesiological techniques were used. Modifications of resections are discussed.
In primary lymphoma of the gastro-intestinal tract radiological and clinical findings are often uncharacteristic for a long time and even tissue biopsy may be difficult to classify pathohistologically. The conclusive diagnosis of this rare entity can be established radiologically only in combination with serological, endoscopic und pathologic findings during the course of the disease.
Surface coils are specially designed radio-frequency receiver coils used for magnetic resonance imaging (MRI) of special anatomical regions, for instance, orbit and knee joint, with a higher spatial resolution than that obtained with conventional MRI techniques. They are designed to fit the anatomical part to be imaged, thus enabling a coil to be placed in close proximity to relevant structures. Surface coils can take these different shapes because they are only used for detecting the MR signal and thus do not need to meet particular design specifications for optimal radio-frequency homogeneity. We report our clinical experience with nearly 100 patients in the first year in the special surface-coil approach of orbit and knee joint.
Based on selected case studies the pathways of spread of malignancies arising from the pelvis are discussed. Secondary involvement of the transverse colon with characteristic lesions at the inferior border may be seen in these cases, caused by metastatic spread via the greater omentum. Ultrasonography and computed tomography may prove this diagnosis by showing peritoneal metastatic spread and tumorous infiltration of the greater omentum.
The difficulties in the differential diagnosis of jaw cysts are demonstrated by 10 selected case studies. Panorama radiographies are basic for radiodiagnosis. Supplementary radiographs, including CT, are often necessary. In general, the final diagnosis can be given after synopsis of clinical, radiographic and patho-histological findings.
A special surface coil was developed with the intention of producing optimal resolution and signal-to-noise ratio for the examination of the knee joint by MRI. Eight volunteers and 25 patients with various abnormalities of the knee have been examined. Normal anatomical structures can be differentiated and there is high diagnostic reliability for lesions of the meniscus, as confirmed by arthroscopy and surgery. Cartilage lesions are less well demonstrated. Total rupture of cruciate ligaments is clearly shown, but partial rupture can often be recognised on the basis of indirect signs only. Good diagnostic results were obtained in cases of osteochondritis dissecans and chondropathia of the patella.
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A retrospective study of 57 patients was made to assess the potential of magnetic resonance imaging (MRI) for demonstrating malignant lymph node disease in comparison with other imaging modalities. All patients were suspected of having lymphadenopathy in cervical, mediastinal or abdominal lymph nodes. MRI was superior in differentiating tumor involved lymph nodes from surrounding structures. On the other hand this advantage was curtailed by the spatial resolution, poorer than CT. In comparison with ultrasound MRI is the better reproducible modality and is independent of patients' constitution. Additionally MRI gives a completer overview, including retrocrural and pelvic lymph nodes. In conclusion the useful routine of ultrasonography first, completed by CT will not be changed by MRI. MRI as an additional modality is only indicated to differentiate enlarged lymph nodes from vascular structures or muscles.
With the advent of ultrasonography and computed tomography in the diagnosis of nodal and/or extranodal manifestation of non-Hodgkin's lymphoma (NHL) lymphomatous involvement of sites other than lymph nodes is seen with increasing frequency. - Review of patients with newly diagnosed or recurrent disease revealed 93 unusual extranodal sites below the diaphragm in peritoneal or retroperitoneal structures or organs. - Concomitant retroperitoneal and/or mesenteric adenopathy was common; extranodal involvement was rarely the only site of initial or recurrent lymphoma.
The reasonable use of computed tomography in the diagnosis of an enlarged retrorectal space was analysed in 92 cases. CT is useful in differentiation of a pathologically enlarged retrorectal space without mucosal lesions of the rectum. It enables the separation between tumourous masses, proliferation of connective tissue (in retrorectal fibrosis or inflammatory disease) and pelvic lipomatosis. If simultaneous mucosal involvement in barium enema or rectoscopy--especially in rectal carcinoma or recurrent carcinoma of the rectum- is found, CT may show the perirectal extension of tumorous masses and thus help to clarify local operability.
Report on the incidence of recurrences, the time necessary for complete remission, and the sites of recurrences in 333 patients with demonstrated lymphogranulomatosis. Suggestion of an examination scheme considering clinical data and laboratory findings for early diagnosis of recurrences. Among the image-producing methods, sonography and CT are of special importance besides thorax examination, lymphography, and bone scintigraphy.
In 1003 patients suffering from bronchial carcinoma the authors examined the type of lymph node spread. Radical lymph nodeectomy takes 30 to 60 minutes more without increasing the survival time, only the rate of regional metastases is diminished. The fate of the patient is dependent on the spread of haemotogenous micrometastases. According to the authors opinion simple extirpation of the regional lymph nodes as an en-bloc-procedure will be sufficient.
In 17 patients, signs of retroperitoneal gas accumulations were assessed on two planes by plain radiographs, and also by means of sonography and computed tomography. In some cases, diagnosis is possible via the plain radiographs if one knows the retroperitoneal compartments and the typical paths of propagation of both gas and inflammatory processes. Provided that conditions of examination are favourable, sonography can help to determine the seat and aetiology of the disease. In any case, however, computed tomography is clearly superior to both methods. Besides enabling the definite identification of gas accumulations, it provides a means for the exact localization in the retroperitoneal area, and in most cases also for arriving at the final diagnosis. This is important for effective treatment planning.
Free or loculate intraperitoneal fluid can easily be detected by ultrasonography or computerized tomography. The differentiation of bile fluid from other liquid collections and the documentation of the presence and extent of a bile leak can be difficult diagnostic problems. In representative case studies the use and the diagnostic limits of ultrasonography and CT in the diagnosis of intraperitoneal bile accumulations are discussed. A diagnostic algorithm including cholescintigraphy for the evaluation of biliary leakage is proposed.
Based on the sonographic findings in 107 cases with proven peritoneal carcinomatosis (PCA) by either gynaecological or gastrointestinal tumors the diagnostic value of ultrasonography and its limitations in differentiation of peritoneal fluid accumulations and masses are presented.
Acute appendicitis is primarily not a radiologically established diagnosis. In atypical abdominal symptoms plain radiographs and additive real-time ultrasonography may often show typical findings especially in complications of acute appendicitis (perforation, abscess formation and ileus). In these cases the differential diagnosis is narrowed and further therapeutic steps may be modified considerably.