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Biomedical subjects

D Benton

Publications and source records attributed to D Benton.

At least 109 records · Page 6Linked to original sources

Blood glucose influences memory and attention in young adults.

There is evidence from animal studies that increased blood glucose levels are associated with improved memory and attention. Although previous studies have found human memory to be facilitated by the administration of glucose, attentional measures have been largely ignored. Therefore the impact of a glucose drink, or a placebo, on the Rapid Information Processing Task and the Stroop Task was examined. The reaction times of those taking the Rapid Information Processing Task were faster both during the baseline period and after a glucose drink if the blood glucose values were high. With the Stroop task the ability to perform the most cognitively demanding sub-test was selectively enhanced if blood glucose values were increasing prior to starting the test. The ability to recall words from a word list was greater if a glucose drink had been consumed, although primary and recency were not differentially influenced. The possibility is discussed that higher levels of brain glucose are associated with better memory and attention.

Adult↗

The impact of raising blood glucose on reaction times.

Although previous studies have demonstrated enhanced mood and memory in humans following the consumption of glucose drinks, the effect of increasing blood glucose levels on other tasks has not received the same attention. In the present study, inspection time was unaffected by glucose drinks and blood glucose levels. However, increasing blood glucose levels resulted in faster decision times when reaction time was measured. It is concluded that speed of processing is faster when the availability of glucose to the brain is increased. The possibility that the glucose-induced improvements in reaction time reflect an increased synthesis of acetylcholine is discussed.

Adolescent↗

Blood glucose and human memory.

As it has been suggested that blood glucose might play a role in the action of some cognitive enhancing drugs, the influence of glucose containing drinks on human memory was examined. In a double-blind study the influence was examined of a drink containing 50 g glucose, or a placebo, on the ability to recall a word list. There was a significant correlation between blood glucose values and the number of words recalled. Those whose blood glucose levels were increasing remembered significantly more words than those whose blood glucose levels were falling. No relationship was found between blood glucose and performance on a test of spatial memory. In a second study blood glucose levels were raised for 2 h by taking a series of glucose-containing drinks. The number of words recalled from a word list correlated significantly with blood glucose levels but not with recall of a Wechsler story. The glucose-induced improvement in memory did not occur only in those whose blood glucose levels were initially low; rather it occurred irrespective of initial blood glucose level.

Adult↗

Is raised blood glucose associated with the relief of tension?

A series of three studies examined the influence of glucose drinks and increasing blood glucose levels on mood. Experiment one considered the short-term effect of a glucose containing drink on mood in young adults: a glucose drink in the morning and higher blood glucose levels were both associated with feeling less tense. Higher blood glucose was also correlated with greater self-reported energy. In the second experiment high blood glucose levels were sustained for 2 hr by repeatedly taking a glucose containing drink. Again higher blood glucose levels were associated with reports of less tension. In a final study subjects were placed in a frustrating situation. The consumption of a glucose drink resulted in fewer negative responses, following a negative statement from the experimenter, in subjects who had fasted over-night. It was concluded that higher blood glucose levels are associated with feeling less tense.

Adaptation, Psychological↗

Myxococcus xanthus encodes an ATP-dependent protease which is required for developmental gene transcription and intercellular signaling.

The bsgA gene of Myxococcus xanthus plays an essential role in the regulation of early gene expression during fruiting body formation and sporulation. bsgA mutants behave as though unable to initiate a required cell-cell interaction and consequently fail to transcribe normal levels of many developmentally induced genes. We determined the nucleotide sequence of bsgA, which predicts a single gene encoding a 90.4-kDa protein. The deduced BsgA protein shares 45 and 48% amino acid identity with the lon genes of Escherichia coli and Bacillus brevis, respectively. The cloned bsgA gene was expressed in E. coli, and the BsgA protein was partially purified and found, like its E. coli homolog, to be an ATP-dependent protease. Thus, the basis for the phenotype of bsgA mutants is likely to be a defect in intracellular proteolysis.

ATP-Dependent Proteases↗

IQ and diet.

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Child↗

Participation in physical activity and cardiovascular fitness have different effects on mental health and mood.

The cardiovascular fitness, blood pressure, resting pulse, lung capacity and body fat of 246 subjects were measured and each subject completed activity, mental health and mood questionnaires. The results of this study support the hypothesis that participation in physical activity, rather than cardiovascular fitness, is the factor associated with better mental health and mood. Higher levels of physical activity were associated with better mood scores unless the individuals were unfit. This research has implications for how physical activity is prescribed; the emphasis needs to be on performing physical activity rather than improving fitness and should not be beyond the physical capabilities of the individual.

Adaptation, Psychological↗

Breakfast, blood glucose and memory.

The hypothesis that blood glucose levels influence memory was re-examined. The performance on two memory tests was quicker when breakfast had been taken, suggesting that the ability to retrieve memories had been facilitated. Performance on a spatial memory test correlated significantly with blood glucose levels.

Adult↗