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Biomedical subjects

D Becker

Publications and source records attributed to D Becker.

At least 307 records · Page 17Linked to original sources

[Combined plastic bridging of a post-traumatic osseous defect of the tibia in the sense of compound osteosynthesis in elderly patients (author's transl)].

The article presents a woman (now 82 years of age) in whom adjustment osteotomy had been performed in order to cope with her proximal fracture of the tibia which had healed in varus position after conservative therapy. After absorption of the bone wedge and loosening of the osteosynthesis material, the defect was filled with bone cement with embedded screws and plates. Three years later, the patient returned for treatment with completely loosened Palacos seal which had perforated distally through the skin and rather broadly. Besides pseudarthrosis, there was also a marked arthrosis of the knee joint. The patient was re-operated, bridging the defect by means of Fracto nets and a bolted Placos seal into which a Sheehan's knee was inserted.

Aged↗

The effects of targeting improvements in urine glucose on metabolic control in children with insulin dependent diabetes.

A treatment program designed to increase the percentage of negative urine tests was implemented using a multiple-baseline across groups design in a sample of 19 families of children with insulin dependent diabetes. The treatment involved instruction in insulin adjustment, decrease in intake of simple sugars and saturated fats, and increase in exercise, along with teaching the parents to support improvements in children's self-regulatory behaviors using a point economy and praise. New procedures designed to measure and reinforce adherence to the urine testing regimen were developed. Results showed significant increases in percentage of negative urines consistent with implementation of treatment across the three treatment groups, which were maintained over the follow-up period. Metabolic measures of control, including glycosylated hemoglobin and serum glucose did not show improvements even though the relationship between the percentage of negative urine tests and glycosylated hemoglobin was very high during treatment.

Behavior Therapy↗

Adrenocortical tumor in a patient with congenital adrenal hyperplasia due to 21-hydroxylase deficiency.

An adrenal cortical tissue tumor developed in a patient with poorly controlled salt-losing congenital adrenal hyperplasia. A 16-year-old girl became progressively virilized from 13 to 16 years of age. Base line serum progesterone, 17-hydroxyprogesterone, and testosterone levels were high and there was a diurnal pattern of the hormones. Initially elevated urinary 17-ketosteroid and serum steroid levels were decreased by high dose dexamethasone therapy, and at laparotomy an adenoma was found in the cortex of the hyperplastic left adrenal gland. It is inferred that persistent adrenocorticotrophic hormone stimulation may result in neoplastic transformation of hyperplastic adrenal cortical tissue in patients with congenital adrenal hyperplasia.

Adenoma↗

Storage of audiometric data - online - with a small computer.

For online storage of audiometric measuring data we use an audiometer with serial operating output, a computer (DEC PDP 11/03), and a graphic terminal (DEC VT 55). The data can be controlled at any given time on the display and read like an audiogram. To transmit the data it is mainly only necessary to activate one button on the audiometer in addition. Pure tone and speech audiograms appear on the display in separate diagrams; in addition, beneath the pure tone threshold the results of the suprathreshold tests and the impedance measurements are indicated. For additional observations three lines are left available. If desired, a computer-supported masking aid can be used; independent of this, cross-heard values and applied masking noise intensities are stored. Paper documentations can achieve success as a hardcopy or as a four-coloured plotter print. Statistical groupings are possible without further processing.

Audiometry↗

Calendar life span versus budding life span of Saccharomyces cerevisiae.

This investigation is concerned with the internal factors governing the life span of individual yeast cells. The life span may be limited either by the number of buds a cell can produce or by internal measurement of metabolic time. The natural relationship between the number of cells a single cell can produce and the passage of time was modified by three different kinds of treatment: (1) by cooling the cells for several hours each day; (2) by preculturing the cells in media which inhibit cell division before allowing logarithmic growth; and (3) by culturing the cells in a medium which reduces the rate of budding. All these methods led to a prolongation of chronological life span, but the life span measured by the number of buddings remained remarkably constant. We therefore conclude that there is some kind of factor involved in the budding process which determines life span.

Cell Division↗

Computerized tomography and pathological correlation in cystic meningiomas. Report of two cases.

Meningiomas have been reported to have associated areas of surrounding low density on computerized tomography (CT). These low-density areas may represent edema, widened subarachnoid spaces, loculated cerebrospinal fluid, demyelination, or adjacent tumor. Two cases are presented in which this adjacent area of low density represented a tumor cyst. Recognition is important as the CT appearance of these lesions may simulate a metastatic tumor.

Humans↗

[The adolescent confronted with hemodialysis and transplantation, psychological problems and developmental factors].

A study has been undertaken of the psychological problems of more than 250 adolescents and young adults with chronic renal failure in a dialysis and transplantation programme. The centre provided treatment and helped the patients to adapt to their illness. As the illness is of indefinite duration observations could be made of the course and the outcome. The individuals reaction to different forms of treatment, the possible final outcome and the institution were studied.

Adaptation, Psychological↗

Hallervorden-Spatz syndrome.

Two siblings with Hallervorden-Spatz syndrome showed striking homotypism and homochronism. Neuropathologic examination and electron microscopic studies were done; neutron activation analysis showed an increase in the uptake of iron in the basal ganglia. Of particular relevance is the application of radioactive iron studies in the clinical course of this syndrome. These studies disclosed an increase in the uptake of iron in the area of the basal ganglia in one sibling and in another isolated patient. This procedure will be helpful toward the clinical diagnosis.

Axons↗