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Biomedical subjects

D Baleriaux

Publications and source records attributed to D Baleriaux.

At least 37 records · Page 2Linked to original sources

[Magnetic resonance imaging (MRI) of cervico-facial tumors].

Magnetic Resonance Imaging (MRI) gives substantial advantages for the study of tumoral extension in the anatomically complex cervico-facial region. The multiplanar approach permits a better analysis of the anatomical relationships of the tumor, including relationships with the vascular structures, without the need for injecting a contrast medium. The method is able to accurately differentiate tissues and is very sensitive for detecting tumoral tissue. Lesions poorly visible with CT, with poor contrast enhancement or lying in a muscular environment, are well demonstrated. Some difficulties remain for obtaining from patient a complete immobility for a long examination. We think MRI gives a substantial benefit for the diagnostic work-up of cervico-facial tumours, and could be the first imaging technique in this area, particularly if further shortening of the examination time is gained with fast imaging methods and if availability of MRI installations is improved.

Head and Neck Neoplasms↗

[Magnetic resonance imaging of the pituitary gland and the sella turcica region. Normal and pathological aspect].

MRI may be presently considered as the optimal imaging technique for the study of the sellar and parasellar region. Excellent anatomic and multiplanar approach, absence of irradiation, spontaneous visualization of vascular elements, absence of artefacts characterize MRI. The normal aspect of the sellar region is first described on both spin-echo, T1 and T2 weighted images. MRI appearance of micro and macroadenomas is described. The use of paramagnetic contrast agents (Gadolinium DTPA or DOTA) is widely accepted as a useful complementary diagnostic tool. Moreover the most commonly encountered lesions of the sellar region are reviewed and their behaviour on MRI discussed. Although MRI is an outstanding imaging technique, particularly useful for the study of the sellar region it must be stressed that MRI lacks of specificity. As a consequence, it is of utmost importance to compare MRI with clinical and biological examinations in order to reach a confident final diagnosis.

Adenoma↗

Argyrophilic breast carcinoma, single metastasis to the pituitary gland.

Five years ago, a 44 year-old woman presented with an apparently localized cancer of the right breast, initially treated by surgery, adjuvant chemotherapy and radiotherapy. After a 4 year disease-free interval, she developed bi-temporal hemianopsy, due to a suprasellar tumor causing compression of the optic chiasma. The tumor was resected by the transsphenoidal route and histological examination revealed neuroendocrine characteristics described as "argyrophilic breast carcinoma". The exceptional association of this peculiar histology for breast cancer with a rare pattern of recurrence (single pituitary metastasis) is worthwhile reporting.

Adult↗

Nervous system manifestations and neuroradiologic findings in acquired immunodeficiency syndrome (AIDS).

We report a series of thirteen patients with nervous system complications out of a total of thirty AIDS patients admitted to our hospital over the last two years for which CT and/or MRI have been performed. Five were homosexual men and eight patients (5 men, 3 women) were of African origin (Zaïre and Rwanda) (n = 5) or had had sexual intercourse with the local African population (n = 3). The nervous system complications encountered included: toxoplasma gondii brain abscess (2 patients); cryptococcus neoformans meningitis + toxoplasmosis (1 patient); toxoplasmosis + lymphoma (2 patients); progressive multifocal leucoencephalopathy (1 patient); lymphocytic meningitis or encephalitis (3 patients); lymphoma (1 patient); polyradiculoneuritis (3 patients). Three of thirteen patients had multiple intracranial abnormalities: one had concomitant intraparenchymal toxoplasma abscess and cryptococcal meningitis; in one patient a lymphoma developed after the successful medical treatment of a toxoplasma abscess; conversely, one patient developed a toxoplasma abscess two years after mediastinal radiotherapy for a systemic non-Hodgkin lymphoma. In conclusion, in our experience, nervous system toxoplasmosis is the most frequent AIDS related CNS complication. Our series demonstrates the high frequency of a second neurological disease occurring either concomitantly or separately. In these cases, while CT may readily identify the intracranial abnormalities, it contributes little towards an etiological diagnosis. Finally, our series illustrates the importance of a central African endemic focus for AIDS.

Acquired Immunodeficiency Syndrome↗

Comprehensive and interpretative radiology of middle ear malformations.

Radiological aspects of middle ear malformations based on the study of 31 observations should be correlated with the modalities of normal and abnormal morphogenesis. This is particularly the case for malformations of the ossicles, which can be classified according their precise branchial origin. Facial nerve malformations, dysgenesis of the footplate and atresia of the external auditory meatus is discussed in relation to normal events of middle ear morphogenesis. Standard histochemical procedures and study of radioactive sulphur uptake in the mouse embryo permit to characterize some factors of middle ear ossicles formation. Study of correlations between radiological features and experimental results reveal that the important factors are: the chronology of morphogenesis; the organization of branchial structures; the patterns of neural crest cells migration; the influence of environmental factors. Furthermore, teratologic features obtained in animals models can be correlated with human syndromes.

Animals↗

The traumatic aspect of ventricular catheterization demonstrated by magnetic resonance imaging.

Five patients who underwent ventricular catheterization for increased intracranial pressure, were studied shortly after operation by two different radiological modalities: Magnetic Resonance Imaging (MRI) and Computed Tomography (CT). MRI showed an important brain edema surrounding the site of ventricular catheterization especially in the frontal area, whereas CT did not demonstrate any anomaly or only a very slight one. This report outlines the traumatic aspect of ventricular puncture and the need for a proper setting at the first essay.

Brain Diseases↗

Thoracic spinal epidural cysts.

Two cases of spinal cord compression by thoracic epidural cysts are reported. The first case, associated with a lipoma, is of a congenital type, while the second illustrates a rare mechanism of spinal cord compression caused by a post-traumatic cyst after stretching of the brachial plexus and tearing of the meningeal sheaths of nerve roots. Computed tomography of the spine is helpful in disclosing the cyst and associated malformation, particularly in congenital cases. The prognosis is good after removing the cyst and closing the fistula communicating with the subarachnoid space. Further surgical treatment may be required in complex congenital malformations.

Adult↗

Comparison of iohexol and ioxaglate for intravenous digital subtraction angiography of the neck and head.

Two hundred patients undergoing intravenous digital subtraction angiography of the cerebral circulation were examined on a random basis with either iohexol 350 mg I/mL or ioxaglate 320 mg I/mL. The two low osmotic media provided equally satisfactory image quality and diagnostic possibilities. No significant differences were found in incidence and severity of adverse reactions.

Carotid Arteries↗