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Biomedical subjects

D B Soll

Publications and source records attributed to D B Soll.

44 records · Page 3Linked to original sources

Diamond-like carbon coating and plasma or glow discharge treatment of mechanical heart valves.

All mechanical heart valves (MHV) are thrombogenic. Application of surface modification technology to reduce the incidence of thrombus formation on MHV is a novel undertaking. This requires collaboration within the bioengineering and cardiothoracic surgery fields. From reviewing results of recent and past investigations, and our own preliminary study with diamond-like carbon coating (DLC) and plasma or glow discharge treatment (GDT) of MHV, we identify and discuss several potentially beneficial effects that may reduce the extent of valve-related thrombogenesis by surface modification. DLC and GDT may affect the surfaces of MHV in many ways, including cleaning of organic and inorganic debris, generating reactive and functional groups on the surface layers without affecting their bulk properties, and making the surfaces more adherent to endothelial cells and albumin and less adherent to platelets. These different effects of surface modification, separately or in combination, may transform the surfaces of MHV to be more thromboresistant in the vascular system.

Animals↗

The use of scleral transplantation in cicatricial entropion and eyelid retraction.

Scleral transplantation has given excellent results in the surgical repair of eyelid problems. The advantages of using scleral transplantation in repairing eyelid retraction are the relative predictability of the final eyelid position and curve and the decreased incidence of repeated retraction. The characteristics of sclera make it a desirable homologous transplant material for use in transplant surgery.

Entropion↗