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Biomedical subjects

D B Paul

Publications and source records attributed to D B Paul.

25 records · Page 2Linked to original sources
PubMed1985

Pelvic lymphadenectomy for carcinoma of prostate.

Pelvic lymphadenectomy was performed in 187 patients as a staging procedure for carcinoma of the prostate. Clinical impression of lymph nodes during dissection appears to be inaccurate in a large number of patients. We therefore believe that if radical surgery is planned for clinically localized tumor, the histologic status of the removed nodes should be confirmed before surgical extirpation of the tumor.

Adenocarcinoma↗
PubMed1985

Textbook treatments of the genetics of intelligence.

Genetics textbooks have been remarkably unaffected by the discovery of fraud in the work of British psychologist Sir Cyril Burt or by the resulting critical review of other classic studies on the genetics of intelligence. Although Burt's name has nearly vanished from current textbooks, his results continue to be cited in textbook discussions of the heritability of intelligence, as do the results of other studies now recognized as methodologically inadequate. Moreover, genetics textbooks consistently employ confused or misleading definitions of the concept of heritability that, together with the reporting of discredited data, perpetuate a fundamentally inaccurate understanding of the genetics of intelligence. This situation is largely attributable to the practice--generic to textbook writing but in this case taken to an extreme--of authors' liberal borrowing from one another or from a few apparently authoritative works (including earlier textbooks). The extent to which authors rely on these sources for their discussions of the genetics of intelligence is apparently a function both of the controversiality of the subject and of authors' technical insecurity, perhaps reinforced by prior assumptions about the influence of genes on variations in intellectual performance.

Genetics, Behavioral↗
PubMed1983

Morbidity from pelvic lymphadenectomy in staging carcinoma of the prostate.

A retrospective review of 150 patients with adenocarcinoma of the prostate was done to determine the morbidity associated with lymphadenectomy performed as an independent procedure. A total of 77 complications, 17 of which were considered major, was noted in 50 patients. Wound drainage and transection of the spermatic cord were associated with increased morbidity. Systemic antibiotic therapy afforded no protection against wound infections, while intraoperative irrigation was protective. Lymphoceles and lower extremity edema occurred infrequently in our series, although only a few patients underwent postoperative pelvic irradiation therapy.

Adenocarcinoma↗
PubMedDate not supplied

Genetic services, economics, and eugenics.

What are the aims of genetic services? Do any of these aims deserve to be labeled "eugenics"? Answers to these strenuously debated questions depend not just on the facts about genetic testing and screening but also on what is understood by "eugenics," a term with multiple and contested meanings. This paper explores the impact of efforts to label genetic services "eugenics" and argues that attempts to protect against the charge have seriously distorted discussion about their purpose(s). Following Ruth Chadwick, I argue that the existence of genetic services presupposes that genetic disease is undesirable and that means should be offered to reduce it. I further argue that the economic cost of such disease is one reason why governments and health care providers deem such services worthwhile. The important question is not whether such cost considerations constitute "eugenics," but whether they foster practices that are undesirable and, if so, what to do about them The wielding of the term "eugenics" as a weapon in a war over the expansion of genetic services, conjoined with efforts to dissociate such services from the abortion controversy, has produced a rhetoric about the aims of these services that is increasingly divorced from reality. Candor about these aims is a sine qua non of any useful debate over the legitimacy of the methods used to advance them.

Eugenics↗