Search PubMed⌕ Search

Biomedical subjects

D B Levy

Publications and source records attributed to D B Levy.

21 records · Page 2Linked to original sources

Menarche: target age for reinforcing sex education for adolescents.

Teenage sexual activity has led to an increasing prevalence of pregnancy and sexually transmitted disease in this age group. Attempts at prevention should begin with education. This study compares the ages of menarche with ages of first intercourse among adolescent females in 1971 and 1976, stratified by ethnic group and residence (urban versus rural). Findings demonstrated that an earlier age at menarche is consistently associated with earlier intercourse. Menarche should therefore be used as a target age for reinforcing and expanding adolescent females' knowledge of risks associated with sexual intercourse.

Adolescent↗

Anaphylactic reaction due to zomepirac.

Zomepirac sodium is a nonsteroidal antiinflammatory drug with potent analgesic properties. Since its introduction in October 1980, this prostaglandin inhibitor has been fairly well tolerated, and little toxicity has been associated with its use. In fact, it was not until April 1981 that the first serious reaction of anaphylaxis was described. Since then six additional cases have been reported to the literature. The manufacturer voluntarily withdrew the agent in March 1983 from the market pending further investigation of these reactions. We describe the case of an additional anaphylactic reaction to zomepirac and review the literature.

Adult↗

Combination dihydroergotamine mesylate and heparin sodium with lidocaine HCl. Pharmacokinetics, mechanism of action, clinical efficacy, and adverse effects.

Dihydroergotamine(DHE)-heparin combination offers a unique treatment modality for the prevention of deep vein thrombosis. The combination appears to affect all 3 limbs of Virchow's triad: hypercoagulability, venous stasis, and endothelial damage. In most efficacy studies, data indicated that the combination of DHE 0.5 mg and heparin 5000 IU was superior to low-dose heparin alone. Even when the efficacy of DHE-heparin was the same as that of heparin alone, the use of the combination allowed for a decrease in the heparin dose required.

Biological Availability↗