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Biomedical subjects

D B HINSHAW

Publications and source records attributed to D B HINSHAW.

At least 37 records · Page 2Linked to original sources
PubMed1961

Nitrofurantoin (Furadantin). Use of intravenous forms in resistant surgical infections: a preliminary report on 25 patients.

Twenty-five patients with severe and unusually resistant bacterial infections were treated with nitrofurantoin given intravenously.Twelve patients were classified as cured and seven as improved. In two cases there was no observable benefit. The other four patients, all moribund at the beginning of nitrofurantoin therapy, died. No significant toxic reaction to the drug was noted except for a tendency to metabolic acidosis in five patients in a state of shock after treatment with nitrofurantoin (Furadantin(R) intravenous solution). In no case was there evidence of impaired hematopoiesis. From this preliminary report it appeared that nitrofurantoin for intravenous use is justified in the treatment of gravely ill patients with surgical infections resistant to other antimicrobial drugs.

Anti-Infective Agents↗
PubMed1958

Marginal peptic ulcer in elderly patients.

Marginal peptic ulceration occurs with sufficient frequency in elderly patients to constitute a real problem. A study was made of 22 patients more than 65 years of age in whom such ulcers developed. Marginal ulcers in elderly patients are frequently associated with dangerous complications such as massive hemorrhage or perforation. Advancing age does not necessarily reduce the tendency to marginal ulcer formation. Such operative procedures as gastroenterostomy without vagotomy, and minimal gastric resection, do not afford adequate protection from marginal ulceration in elderly patients. When marginal ulcers occur in elderly patients, adequate gastric resection (70 to 75 per cent) or vagotomy in combination with resection is usually necessary.

Aged↗