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Biomedical subjects

D B Green

Publications and source records attributed to D B Green.

At least 19 recordsLinked to original sources
PubMed1995

Evidence for sexual and mother-to-child transmission of human T lymphotropic virus type II among Guaymi Indians, Panama.

Guaymi Indians, a non-intravenous drug-using population in which human T cell lymphotropic virus type II (HTLV-II) is endemic, were studied in Changuinola, Panama, to identify the prevalence and modes of transmission of HTLV-II. A population-based survey showed that 352 (9.5%) of the 3686 participants were seropositive for HTLV-II. Infection rates were the same for male and female subjects and increased significantly with age, beginning in young adulthood. HTLV-II infection status was highly concordant among spouses (P < .001) and between mother and child; of children aged 1-10 years, 36 of 219 born to seropositive mothers were seropositive compared with 3 of 997 born to seronegative mothers (P < .001). The strong associations of HTLV-II infection with age and with an infected spouse in adults and of infection in children with infection in their mothers strongly suggest sexual and mother-to-child transmission of HTLV-II in this population.

Adolescent↗
PubMed1994

Utilization of ketorolac tromethamine for control of severe odontogenic pain.

Ketorolac tromethamine (KT) (Toradol, 60 mg to 2 ml), an injectable nonsteroidal anti-inflammatory drug, was compared with a placebo (sodium chloride, 0.9%) for analgesic effects in patients presenting with severe odontogenic pain. Utilizing a double-blind protocol, KT and placebo were administered and evaluated. Forty patients presenting with severe odontogenic pain (75 to 100 mm and above utilizing the visual analog scale of 100 mm) recorded their visual analog scale score once every 10 min for 90 min after injection of either KT or placebo and before initiating traditional incision and drainage, endodontic therapy, and/or extraction. Results indicate that KT patients had significantly less pain from 20 to 90 min postadministration than those receiving placebo. By the 90-min period, KT patients were reporting negligible discomfort. Observed side effects included lightheadedness and injection site pain. It was concluded that KT effectively reduces severe odontogenic pain within 40 min after administration in human subjects, with minimal side effects.

Adult↗
PubMed1994

Unusual pattern of pulp canal obliteration following luxation injury.

Pulp canal obliteration can occur as a result of tooth injury. A case report is presented in which a 6-yr-old patient developed partial pulp canal obliteration of a maxillary central incisor 9 months after luxation injury. The mineralization created unusual canal morphology which presented some difficulty in endodontic treatment of the tooth.

Child↗
PubMed1993

Failure to detect human T-lymphotropic virus antibody in wild-caught New World primates.

We conducted a study to look for a simian counterpart of human T-lymphotropic virus (HTLV) in wild-caught monkeys in the Republic of Panama. Serum specimens were obtained from 102 monkeys (Ateles fusciceps, n = 75; Alouatta villosa, n = 18; and Cebus capucinus, n = 9) captured in Panama's Darien rain forest in 1979-1980. Specimens were screened for HTLV antibody by enzyme-linked immunosorbent assay, and reactive specimens were further tested by Western blot. None of the 102 specimens were seropositive for HTLV. Our findings provide no evidence for an HTLV-like virus in New World primates from Panama, but the sample size was small, and further studies are warranted.

Alouatta↗
PubMed1992

Orofacial and craniofacial pain. Primary care concerns.

A patient who experiences an acute episode of oral or facial pain is likely to consult a primary care physician. Dr Green reviews the basic information needed to distinguish among the more common types and causes of such pain. Once the pain's source is determined, treatment can be prescribed or an appropriate referral made.

Diagnosis, Differential↗
PubMed1990

Effect of sodium hexanitrocobaltate (III) decomposition on its staining of intracellular potassium ions.

The effect was examined of the chemical decomposition of the potassium stain sodium hexanitrocobaltate (III) (SHC), on its ability to produce stain granules of consistent size that could be used to estimate the K+ contents of stomatal guard cells. Stomata in detached epidermis from leaves of Vicia faba (fava bean) were stimulated to accumulate K+ by treating them with fusicoccin. Stomatal apertures and the fraction of guard cell area covered by K+ precipitate granules (K+ score) were measured by digitizing photographic enlargements, and K+ scores were correlated with the age of stain that had been stored either in open or closed containers. The ability of stain aged in open containers to produce consistent fractional cell coverage was compared to 1) the ability of identically treated stain to precipitate K+ from solutions of KCI, and to 2) the kinetics of decomposition of SHC. It was found that the fractional coverage of guard cells of stomata opened to the same apertures decreased with a first order rate constant of 2.3 x 10(-5)/sec. The mass of precipitate formed by treatment of KCl solutions was unchanged for 2 hr after initial preparation of the SHC, and decreased thereafter with a first order rate constant of 1.0 x 10(-5)/sec. When stored in tightly sealed containers, nearly 100 hr were required for an occasionally opened bottle of SHC to decay to the same efficacy as a solution left open to the air for 8 hr.

Cobalt↗
PubMed1974

Relationship between the concentration of bacteria in saliva and the colonization of teeth in humans.

The relationship between the salivary concentration of bacteria and their number that can be recovered from tooth surfaces has been studied in 12 human subjects. The mean salivary concentration of naturally occurring Steptococcus mutans and lactobacilli, determined on selective media, was 3.7 x 10(5) and 3.8 x 10(5) colony-forming units (CFU) per ml, respectively. In subjects with salivary concentrations of S. mutans of about 10(4) CFU/ml or less or about 10(5) CFU/ml or less of lactobacilli, these organisms could not be isolated from cleaned teeth after 2 to 3 h of oral exposure. In experiments with streptomycin-labeled S. sanguis cells held in the mouth for 15 min, the minimal salivary concentration required for their recovery from the teeth was about 10(3) CFU/ml. Both S. mutans and lactobacilli were found to be highly localized on teeth. This evidence suggests that the concentrations of S. mutans and lactobacilli generally present in saliva are insufficient for the initiation of their firm attachment to relatively nonretentive tooth surfaces. The low efficiency of their intraoral spread, as suggested by their highly localized distribution on teeth, or of their transmission between subjects may be essentially due to the interrelated factors bacterial affinity and number of colony-forming units available for attachment.

Adult↗
PubMed1971

The liaison.

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Education, Dental↗