Biomedical subjects
D B Gordon
Publications and source records attributed to D B Gordon.
Understanding equianalgesic dosing.
Over the past several years, improving pain management has become a major initiative. Nurses play a vital role in this effort. To be most effective in this pain relief role, nurses need to develop a clearer understanding of the opioid analgesics and how to use them. The purpose of this article is to outline basic questions that are helpful as one considers either changing routes of opioid analgesic administration or changing drugs. Use of the equianalgesic table is discussed with specific examples of use in clinical practice.
The role of renin substrate in hypertension.
A positive correlation between blood pressure and renin substrate concentration is found in a wide variety of conditions in human beings and in animal experiments. The evidence concerning this relationship is reviewed and the exceptions are discussed. The frequent positive correlation between renin substrate and elevated blood pressure suggests that increased renin substrate concentration may be a causal factor in hypertension.