Biomedical subjects
D B Edwards
Publications and source records attributed to D B Edwards.
Collagenous colitis and histiocytic lymphoma.
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Prostaglandin and clostridial vaccination.
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Postoperative pneumomediastinum and pneumothorax following orthognathic surgery.
Pneumomediastinum and pneumothorax are rare complications in the postoperative oral and maxillofacial surgery patient. Review of the sequence of events relating to these two life-threatening conditions emphasizes the importance of awareness of the clinical presentation and pathophysiology of these conditions as well as the need for judicious pulmonary physiotherapy in the intubated patient.
Fracture of the glenoid fossa and dislocation of the mandibular condyle into the middle cranial fossa.
Reported cases of dislocation of the mandibular condyle into the middle cranial fossa have been rare, and treatment modalities have varied. The case presented represents an instance of successful closed reduction. Numerous factors should be considered when determining the technique of reduction. Primary goals in selecting the method of treatment are stabilization of the neurologic status, control of the bone fragments in the brain, reduction of the occlusion, maintenance of ramus height for facial symmetry, preservation of growth potential, and assurance of satisfactory long-term function of the mandible.
Be alert for symptoms of malignant hyperthermia.
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Long-term feeding study on disodium 5-ribonucleotide in dogs.
Groups of 4 male and 4 female Beagle dogs were fed for 2 years on diets containing 0 (control), 0.1, 1.0 and 2.0%, respectively, of disodium 5'-ribonucleotide (a 50 : 50 mixture of disodium 5'-inosinate and disodium 5'-guanylate). The mean daily intakes of the 3 test groups ranged during the experiment from 0.04-0.03, 0.48-0.26 and 0.93-0.51 g/kg, respectively. No effects attributable to treatment were found in mortality, food consumption, water consumption, bodyweight gain, ophthalmoscopy, clinical signs, haematology, serum chemistry (other than allantoin levels), organ weights, macroscopic pathology or histology, Small differences were observed between mean values in treatment and control dogs for serum allantoin but there was no indication of any persistent significant difference throughout the 2-year study. In a 6-week preliminary test, dietary levels of up to 10% disodium 5'-ribonucleotide were without detectable adverse effect upon beagle dogs of either sex.