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Biomedical subjects

D Apel

Publications and source records attributed to D Apel.

40 records · Page 3Linked to original sources
PubMedDate not supplied

[Prognostic importance of DNA histograms of bone marrow cells in acute myeloblastic leukemias].

DNA histograms were studied in bone marrow cells in 25 patients with acute myeloblastic leukaemia before starting treatment. It was found that patients with complete remission showed a significantly higher proportion of cells in phase S of the cellular cycle (22 +/- 3%) than patients who failed to achieve remission (12 +/- 4%). Assessment of DNA citrograms of bone marrow cells may be one of prognostic factors in acute myeloblastic leukaemia.

Adolescent↗
PubMedDate not supplied

[Treatment of acute leukemias in adults. II. Preliminary analysis of the treatment results according to AR and RAMP programs].

Thirty patients with acute non-lymphoblastic leukaemia were treated. They were randomly assigned to treatment according to programme AR (14 patients) and RAMP (16 patients). The groups were comparable for age and haematological state. Complete remission was obtained in 7 patients out of 14 treated by the AR programme and 6 out of 16 treated by the RAMP programme. The median duration of complete remission is as yet 15 weeks and 16 weeks respectively. The toxic side effects during treatment by the AR programme was statistically significantly higher than in the treatment by the RAMP programme. In the first group 42.8% of early deaths occurred, while in the second group 6.2% patients died early.

Acute Disease↗
PubMedDate not supplied

[Treatment of acute leukemias in adults. IV. Treatment results on 375 patients at 9 hematology centers].

On the basis of standardized protocols of the therapeutic results of acute non-lymphoblastic leukaemias in adults sent to the Institute of Haematology in Warsaw from 8 haematological centres in Poland it was demonstrated that complete remission occurred in 34.4% of patients (129 out of 375 cases). The mean survival time of the patients treated intensively according to programmes I, II, III and IV 8.6 months, those of patients with complete remission - 13.5 months, patients without complete remission - 3.7 months. The most frequent cause of death (82.5%) were infections and/or haemarrhagic diathesis.

Acute Disease↗