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Biomedical subjects

D Allard

Publications and source records attributed to D Allard.

At least 73 records · Page 4Linked to original sources
PubMed1983

[Rupture of the left subclavian artery associated with fracture of the 1st rib].

Treatment in a case of partial rupture of the subclavicular artery, provoking subacute ischemia of the upper limb and associated with a fracture of the first rib, was by sternoclavicular disinsertion and resection-suture. The importance of systematic investigation of possible subclavicular lesions in patients with fractured first ribs is emphasized, both during the initial and follow-up examinations. The presence of a fracture of this type has little influence on the classical surgical attitude adapted, apart from the possible need for resection of the first rib.

Arm↗
PubMed1982

Assignment of human uroporphyrinogen I synthase locus to region 11qter by gene dosage effect.

Recently Meisler et al. (1980) reported the results of mouse/human somatic cell hybrid studies which indicated that the locus for human uroporphyrinogen I synthase (UPS) (EC 4.3.1.8) maps to chromosome 11. To evaluate further this assignment we have children with a trisomy of the region 11qter. We confirm the results of Meisler et al. (1980) and demonstrate that uroporphyrinogen I synthase activity is increased by a factor of 1.5 in trisomy 11qter. In erythrocytes of one child with a trisomy 11p, the expression of this enzyme was normal.

Adult↗
PubMed1980

[Renovascular hypertension in a child, originating in a lower pole aberrant renal vessel dysplastic stenosis (author's transl)].

Renovascular hypertension in a 15-years-old girl, originating in a lower pole aberrant renal artery stenosis by fibromuscular hyperplasia. Microsurgical management by polar artery reimplantation in the renal artery. Unknown evolutivity and diffusion of arterial dysplasias explain the more and more distal repairs reported in literature concerned with renovascular hypertension in infancy and childhood. Nephrectomy and segmental resection are now only done when revascularization is not possible.

Adolescent↗
PubMed1978

[Rapid column chromatography of blood amino-acids from a paper sample (author's transl)].

Authors propose a method permitting rapide quantitative analysis of blood amino-acids from a blood sample on paper. The amino-acid analyser was equiped with two columns of different lenght and diameter, one (0.5 x 30 cm) permitting rapid detection (complete chromatography in 110 minutes), the other (0.63 x 35 cm) permitting a quantitative study of amino-acidopathies (complete chromatography in 240 minutes). The apparatus and the program of elution proposed have the advantage of being adaptable without any other modification than the time of passage of the reagents to very rapid analysis of amino-acid groups and classical analysis of samples of serum and urine.

Amino Acids↗
PubMed1975

Bovine adrenal medullary chromogranin A: studies on the structure and further evidence for identity with dopamine-beta-hydroxylase subunit.

1. Chromogranin A was purified by the use of polyacrylamide gel electrophoresis. The amino acid composition of chromogranin A appeared to be nearly identical to that reported by other investigators and, moreover, was confirmed to be similar to that of dopamine beta-hydroxylase. 2. Dansyl-end group analysis revealed the presence of leucine as the only amino-terminal residue and quantitative estimations showed the presence of two leucine residues per molecule of 77 000 molecular weight. 3. Tryptic and CNBr patterns were obtained. Data are in good agreement with the concept of two nearly identical polypeptide chains per chromogranin A molecule of mol. wt 77 000. Patterns were compared with those obtained in parallel dopamine beta-hydroxylase and support the idea that chromogranin A and the dopamine beta-hydroxylase subunit are identical. Digestion with leucine amino peptidase gave further additional evidence for this suggestion. 4. Chromogranin A appeared to be free of carbohydrates. No cross-reaction was detected between chromogranin A and rabbit antibody against bovine adrenal dopamine beta-hydroxylase.

Adrenal Medulla↗