Biomedical subjects
D Alberti
Publications and source records attributed to D Alberti.
A cause of late graft dysfunction after liver transplantation in children: de-novo autoimmune hepatitis.
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Circulating EBV-DNA in the monitoring of EBV infection in pediatric liver transplant recipients.
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Chlorthalidone alone or in fixed combination with slow-release metoprolol in the management of arterial hypertension: a long-term study of 545 patients.
In a double-blind trial, 545 out-patients with essential hypertension received 25 mg/day chlorthalidone alone (274 patients) or in fixed combination with 200 mg/day slow-release metoprolol (271 patients) for 8 weeks. Both treatments significantly (P less than 0.001) decreased systolic and diastolic blood pressure; 45.6% of patients receiving chlorthalidone and 82.5% receiving combined therapy had a diastolic blood pressure of less than 95 mmHg. Patients not controlled by chlorthalidone or chlorthalidone plus metoprolol subsequently received chlorthalidone plus metoprolol (137 patients) or chlorthalidone plus metoprolol plus a third drug (34 patients), respectively, for 8 weeks. A total of 79.5% of patients receiving chlorthalidone plus metoprolol and 61.8% receiving chlorthalidone plus metoprolol plus a third drug had a diastolic blood pressure of less than 95 mmHg. Only 5.9% of patients experienced mild to moderate side-effects. Plasma potassium levels significantly (P less than 0.01) decreased during the first 8 weeks only. It is concluded that a diuretic alone or in fixed combination with a beta-blocker is effective in the long-term treatment of arterial hypertension.
[Saphenous vein stripping in an outpatient service. 800 cases].
During the period from January to June 1991, 800 patients with varicose veins of the legs underwent, without hospitalisation, stripping of the saphenous vein, multiple phlebectomies by micro-incisions using the Muller technique and elastic compression. Careful patient selection, thorough pre-operative evaluation and perfect surgical technique made it possible to perform the procedure on an out-patient basis and in addition to obtain a good functional result and a very good esthetic result.
Hemodynamic changes in global and regional left ventricular function induced by nitroglycerin. An assessment with 195mAu radionuclide ventriculography.
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[Evaluation of the Doppler-pulse volume recorder in Raynaud's phenomenon].
A study was made of 15 patients (10 female and 5 male), between the age of 18 and 65 years, in order to assess the diagnostic efficacy of the combined Doppler-P.V.R. (Pulse Volume Recorder) technique when examining Raynaud's phenomenon. The patients in the study had suffered for at least a year from recurrent episodes of Raynaud's phenomenon and were compared with 15 normal non-smokers. The patients were given a Doppler and plethysmograph exam with P.V.R. in basal conditions and following heat stimulus. It can be said that while the Doppler exam supplies data that is compatible with the variations in peripheral resistance encountered in Raynaud's phenomenon, P.V.R., although able to give useful information on the general condition of the segment examined, does not yet provide exact data on account of the difficulty in interpreting the graph obtained. Interpreting P.V.R. data can be facilitated by combining P.V.R. with heat test.
[Doppler diagnosis in the localization of incompetent perforating veins].
If persistent or recurring varicosis is to be avoided, it is vital to locate the incontinent perforating veins in patients with venous insufficiency of the lower extremities. This is the case wherever surgery, sclerotherapy or the use of elastic support is required and especially in the absence of the normal signs of diseased deep veins, such as stasis, dermatitis or ulcerations. The inadequacy of clinical examination or certain instrumental techniques in evidencing the largest possible number of incontinent perforating veins is demonstrated. Personal experience of Doppler testing at a Phlebology Clinic is then presented and it is pointed out that the accuracy of this technique depends essentially on the examiner's experience. Correctly performed the technique gives over 90% accuracy in the preoperative diagnosis of incontinent perforating veins.
[Diagnostic possibilities of a Doppler-Pulse Volume Recorder in deep venous thrombosis].
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[The laparoscopic treatment of Hirschsprung's disease].
Swenson's procedure, first described in 1948 for Hirschsprung's disease, consists in resection of aganglionic intestine and distal colo-anal anastomosis provided a precise dissection of extra peritoneal rectum. Potential jeopardy of pelvic vessels and nerves stimulated alternative surgical techniques to prevent complications on bladder and genital function. We performed in laparoscopy Swenson's procedure after Toupet, taking advantage from closer view and magnification of this technique, in a 15 months girl. Laparoscopy simplified and made safer pelvic dissection and resulted in a better postoperative period and cosmetic outcome.