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Biomedical subjects

D Abelson

Publications and source records attributed to D Abelson.

At least 19 recordsLinked to original sources

Stereophonic stethoscope with teaching attachment.

A stethoscope is described in which stereophonic auscultation is achieved by attaching a sound-conducting tube and chest piece to a 2-way stopcock close to the main binaural. In the monophonic mode, a second binaural and conducting tube can be attached via a Y-connector close to the chest piece, permitting 2 observers to listen simultaneously.

Auscultation↗

A work-sampling tool to measure the effect of electronic medical record implementation on health care workers.

This article presents baseline work sampling data from an outpatient oncology clinic prior to an electronic medical record implementation. The physicians and medical office assistants spent 29% and 39% of their time, respectively, entering and retrieving information from medical records. The physicians and medical office assistants spent 43% and 17% of their time, respectively, on direct patient contact. Using scheduled outpatient counts to measure the productivity of the physicians and medical office assistants failed to capture 19% and 29% of their workload.

Ambulatory Care Information Systems↗

Diagnostic value of the penile pulse and blood pressure: a Doppler study of impotence in diabetics.

Penile pulses were palpated and brachial, penile and popliteal pressures were measured with the Doppler technique in 29 normal subjects and in 15 impotent diabetics. The pulses were palpable in all normal subjects but not in 6 diabetics. The penile blood pressure was obtainable in all the normal subjects but not in 2 diabetics. Using the penile pulse data and a comparison of the penile with the brachial systolic pressures, 2 or possibly 3 grades of penile ischemia are definable, providing a measure of pelvic vascular insufficiency.

Adult↗

Spectral and biological changes induced in nicotinic acid and related compounds by ultraviolet light.

1. Irradiation of nicotinic acid, nicotinamide, nicotinamide N-oxide, N'-methyl-4-pyridone-3-carboxamide, reduced nicotinamide-adenine dinucleotide and pyridine with ultraviolet light at 253.7mmu leads to striking spectral changes. 2. Nicotinic acid and nicotinamide are broken down to photosensitive intermediates which in turn undergo photodecomposition. 3. A major photoproduct of [7-(14)C]nicotinic acid is radioactive and absorbs ultraviolet light, but is inactive as a growth factor for Candida pseudotropicalis. 4. Irradiation of nicotinamide gives rise to small quantities of a biologically active photoproduct having the same R(F) as nicotinic acid. A second photoproduct is also formed, but its identity has not yet been established. 5. Irradiation of nicotinamide N-oxide leads to the formation of several photoproducts, one of which has the same R(F) as nicotinamide, absorbs ultraviolet light, and is biologically active. 6. Evidence is presented that irradiation of ethanolic solutions of N'-methyl-4-pyridone-3-carboxamide gives rise to acetaldehyde. 7. Irradiation of reduced nicotinamide-adenine dinucleotide in the presence of acetaldehyde leads to the formation of oxidized nicotinamide-adenine dinucleotide, which in turn can break down to nucleotide and/or nucleoside (depending on the conditions of the reaction). 8. The quantum yields of photolysis and the molar photosensitivities have been determined for N'-methyl-4-pyridone-3-carboxamide and nicotinamide N-oxide. 9. The possible biological significance of these photoreactions is discussed in relation to photosynthesis, visual-pigment metabolism and ultraviolet-light-induced cell damage. 10. A four-step theory is presented for the biochemical evolution of oxidation-reduction systems, involving photoactivated transformations of pyridine derivatives.

Chromatography↗