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Biomedical subjects

D A Witzel

Publications and source records attributed to D A Witzel.

At least 37 records · Page 2Linked to original sources
PubMed1977

Pathology of subacute bitterweed (Hymenoxys odorata) poisoning in sheep.

Subacute bitterweed (Hymenoxys odorata) poisoning was produced in sheep by force feeding them ground plant material (1 gm/kg/day) for 15 days. Five sheep died and two became moribund and were killed at the end of the experiment. The forestomach and abomasum were severely congested and occasionally eroded on the mucosal surface. There was an accumulation of edematous fluids along the rumino-reticular folds and ruminal sulci. Gaseous and fluid distension of the forestomachs, abomasum and cecum was a consistent finding. The gall bladder was greatly distended and occasionally the mucosa was sprinkled with petechiae. The most common finding was severe glomerulonephrosis characterized by proteinaceous casts, swollen and degenerated glomerular tufts and degeneration and necrosis in the inner renal cortex and outer medulla. Mild to moderate toxic hepatosis, characterized by vacuolar degeneration of hepatocytes primarily around the central vein, was consistent.

Abomasum↗
PubMed1976

Arsanilic acid-induced blindness in swine: electroretinographic and visually evoked responses.

Arsanilic acid (1,000 ppm) caused blindness in pigs within 25 to 30 days. The visually evoked response was "nonrecordable" in blind pigs, but was consistently recordable in normal pigs. The electroretinographic response was recordable in both normal and blind pigs, and significant differences were not apparent between results of tests of the 2 groups. Optic disk atrophy was noted ophthalmoscopically; lesions of the optic nerve are probably responsible for the nonrecordable visually evoked response.

Aniline Compounds↗
PubMed1976

Scleral contact lens electrodes for electroretinography in domesticated animals.

Contact lens electrodes are necessary to produce a high quality electroretinogram. Comparison of the electroretinogram recorded with the contact lens electrode and a needle electrode showed a great difference. Contact lens electrodes showed a 50 percent or greater amplitude and less artifacts. This report details the procedure for construction of the contact lens electrodes for domestic animals.

Animals↗
PubMed1976

Acquired coagulation factor X activity deficiency connected with Hymenoxys odorata DC (Compositae), bitterweed poisoning in sheep.

An acquired coagulation factor X activity deficiency was demonstrated in sheep fed Hymenoxys odorata, bitterweed plant. All coagulation tests were normal before the sheep were given the plant material. All tests involving the function of factor X, including a specific factor assay, became abnormal after the sheep were given bitterweed. Other specific factors remained within normal limits. The presence of an inhibitory activity could not be shown.

Animals↗
PubMed1975

Partial lobectomy of bovine liver: a new biopsy technique.

A surgical technique has been developed for partial lobectomy of the bovine liver to obtain greater than 25 gram liver samples. Vertical mattress sutures, backed with plastic tubing, were replaced in the liver near the incision line to provide hemostasis. Hemostasis of the cut surface of the liver was adequate in each case. Postoperative recovery was uneventful and only minor adhesions were found later by laparotomy and at necropsy.

Anesthesia, Inhalation↗
PubMed1973

Passive transfer of johnin hypersensitivity with reactivity resembling clinical paratuberculosis in calves.

Whole blood, white blood cells, plasma, and "febrile plasma" from an artificially hypersensitized bull were transfused, via catheter, into the mesenteric arteries of calves. After 1 to 3 days, the hypersensitivity of each calf was determined by the intra-arterial administration of johnin. Fever and diarrhea followed johnin administration in the calves that had been given whole blood or white blood cells, and diarrhea followed johnin administration in one calf that had been given plasma. Fever and diarrhea developed rapidly in the calves given "febrile plasma." The results provided additional evidence that the fever and diarrhea of bovine Johne's disease are hypersensitivity phenomena which can be successfully transferred to calves and that the febrile response is cell-mediated; evidence that humoral antibody is involved is suggestive but not convincing.

Animals↗