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Biomedical subjects

D A Prince

Publications and source records attributed to D A Prince.

At least 163 records · Page 9Linked to original sources

Thalamocortical relay neurons: antidromic invasion of spikes from a cortical epileptogenic focus.

Thalamocortical relay neurons whose axons project into a penicillininduced cortical epileptogenic focus generate bursts of action potentials during spontaneous interictal epileptiform discharges. These bursts originate in intracortical axons and propagate antidromically into thalamic neurons. Repetitive spike generation in cortical axons and presynaptic terminals could produce a potent excitatory drive and contribute to the generation of the large depolarization shifts which are seen in cortical elements during focal epileptogenesis.

Action Potentials↗