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Biomedical subjects

D A Peters

Publications and source records attributed to D A Peters.

79 records · Page 5Linked to original sources
PubMedDate not supplied

Early behavioral and catecholaminergic effects of 6-hydroxydopamine and guanethidine in the neonatal rat.

New born rats received 7 consecutive daily injections of 6-hydroxydopamine (6-OHDA) or guanethidine. Locomotor activity, measured at 3 day intervals, was differentially affected by these drugs, although neither drug elimination a characteristic pattern of ontogeny of locomotor activity. Differing neurochemical effects were also observed. 6-OHDA decreased tyrosine hydroxylase activity in cortex and cerebellum, increased it in the brainstem and had no effect on the hypothalamus. Guanethidine slightly elevated enzyme levels in all four brain regions, with the elevation in brainstem significant at 16 days of age. Regional brain changes in enzyme activity after 4 daily 6-OHDA injections beginning at 1, 5 or 9 days of age indicated that toxic effect of 6-OHDA upon catecholaminergic neurons was age dependent. These data are not consistent with a simple interpretation either in terms of maturational changes in blood brain barrier permeability to 6-OHDA or neuronal uptake of the drug. Further analyses of brainstem areas indicated that the increased brainstem enzyme activity after 6-OHDA was restricted to the pons.

Aging↗
PubMedDate not supplied

Measuring the essence of nursing: a guide for future practice.

Today's changing health care environment presents nursing with the opportunity to expand its role in the health care system. With this opportunity, issues of appropriate education, delegation of supplemental activities to nonprofessionals, and cost of nursing services become significant. Satisfactory resolution of these issues will require a clearly articulated language for what nursing does so that services can be well defined in some way other than a medical model. Once there are clear definitions, competencies for education can be established, decisions regarding delegation of activities can be made, and costs can be assigned. This article describes the use of the Community Health Intensity Rating Scale (CHIRS) as a beginning point for resolving these issues. The CHIRS is a reliable and valid patient classification tool developed to measure the needs of clients of community health nurses as a basis for projecting agency resources required to address those needs. Data elements in CHIRS offer a nursing perspective that incorporates environmental, psychosocial, and health management concerns; more specific definitions of the content and context of care; and an expanded basis for defining resource consumption.

Clinical Competence↗
PubMedDate not supplied

An assessment guide for community health nurses.

An assessment tool based on the Omaha Classification System broadens the focus of nursing diagnosis to encompass the cultural and sociological aspects of each area of patient assessment.

Community Health Nursing↗
PubMedDate not supplied

Unity of purpose.

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American Nurses' Association↗
PubMedDate not supplied

Development of a community health intensity rating scale.

The purpose of this study was to develop and validate a patient classification method for community health that would enable the categorization of patients based on their nursing care requirements. The Community Health Intensity Rating Scale (CHIRS) was developed by integrating nursing theory with nursing practice. Groups of nurse experts in community health developed prototype definitions for 15 community health parameters that incorporated both patient characteristics and critical indicators of care as descriptors of nursing care requirements. The tool was then pilot tested using staff nurses from three home health agencies. Validation of the tool was accomplished by a retrospective rating of 560 charts from two home health agencies. By quantifying the CHIRS score using nursing visits as a measure of resource consumption, it was possible to show that nursing resource consumption increased with each increasing level of CHIRS rating. Reliability and validity were established for the tool.

Adolescent↗